Preference, Satisfaction and Ease of Use of Genuair® (Pressair™) and Breezhaler® (Neohaler™) Inhalers in Patients With COPD

NCT ID: NCT01915784

Last Updated: 2015-05-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

128 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-07-31

Study Completion Date

2013-10-31

Brief Summary

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Preference study: Genuair® (Pressair™) vs Breezhaler® (Neohaler™) inhalers in patients with COPD

Detailed Description

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Conditions

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Chronic Obstructive Pulmonary Disease (COPD)

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Blinding Strategy

NONE

Study Groups

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Group A

Genuair® (Pressair™) first; Breezhaler® (Neohaler™) second

Group Type EXPERIMENTAL

Genuair®

Intervention Type DEVICE

Inhaler with placebo only. Once daily, for 14 days.

Breezhaler®

Intervention Type DEVICE

Inhaler with placebo only. Once daily, for 14 days.

Group B

Breezhaler® (Neohaler™) first; Genuair® (Pressair™) second

Group Type EXPERIMENTAL

Genuair®

Intervention Type DEVICE

Inhaler with placebo only. Once daily, for 14 days.

Breezhaler®

Intervention Type DEVICE

Inhaler with placebo only. Once daily, for 14 days.

Interventions

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Genuair®

Inhaler with placebo only. Once daily, for 14 days.

Intervention Type DEVICE

Breezhaler®

Inhaler with placebo only. Once daily, for 14 days.

Intervention Type DEVICE

Other Intervention Names

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Pressair™ Neohaler®

Eligibility Criteria

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Inclusion Criteria

* Adult male or female patients aged ≥40 years with stable moderate-to-severe COPD according to the GOLD Guidelines classification (grades II and III): forced expiratory volume in 1 second (measured between 10 to 15 minutes post-inhalation of 400 μg of salbutamol) is 30%≤FEV1\<80% of the predicted normal value
* Patients naïve to both study inhaler devices, Genuair® and Breezhaler®, for at least 2 years
* Agreement to participate and voluntarily sign the informed consent form

Exclusion Criteria

* Patients with other clinically significant uncontrolled chronic diseases, particularly body malformations or diseases affecting coordination and/or motor system
* Patients unable to read product package instructions and answer patient reported questionnaires (PASAPQ)
* Patients with any other serious or uncontrolled mental health problems
* Patients currently participating in other randomised clinical studies
* Patients with COPD exacerbation within 6 weeks before Visit 1 and patient hospitalised for COPD exacerbation within 3 months prior to Visit 1
* Patients with any other conditions that, in the investigator's opinion, might indicate the patient to be inappropriate for the study
* Patient likely to be uncooperative
Minimum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Forest Laboratories

INDUSTRY

Sponsor Role collaborator

Almirall, S.A.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Jordi Estruch, MD

Role: STUDY_DIRECTOR

Almirall, S.A.

Locations

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Almirall investigative site 2

Berlin, , Germany

Site Status

Almirall investigative site 1

Munich, , Germany

Site Status

Almirall investigative site 3

Barcelona, , Spain

Site Status

Almirall investigative site 4

Palma de Mallorca, , Spain

Site Status

Almirall investigative site 5

Glasgow, , United Kingdom

Site Status

Almirall investigative site 6

Newcastle upon Tyne, , United Kingdom

Site Status

Countries

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Germany Spain United Kingdom

Other Identifiers

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M/34273/41

Identifier Type: -

Identifier Source: org_study_id