The Effect Methylphenidate Hydrochloride on Pain and Auditory Sensitivity in Healthy Subjects
NCT ID: NCT01914822
Last Updated: 2017-09-12
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE2
41 participants
INTERVENTIONAL
2013-07-31
2014-09-30
Brief Summary
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2. To examine if Ritalin analgesic effect is a pain specific phenomenon or a part of a broader, non-specific effect on high mental functions.
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
CROSSOVER
TREATMENT
DOUBLE
Study Groups
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methylphenidate hydrochloride
The study will include two sessions which will be conducted at the same time of the day, one week apart from each other. Each session will last approximately 6 hours. In each session subjects will be exposed to baseline experimental pain models and auditory tests. Then they will receive either one MP SR 20 mg tablet or an identical looking placebo.
methylphenidate hydrochloride
Sugar pill
The study will include two sessions which will be conducted at the same time of the day, one week apart from each other. Each session will last approximately 6 hours. In each session subjects will be exposed to baseline experimental pain models and auditory tests. Then they will receive either one MP SR 20 mg tablet or an identical looking placebo.
Sugar pill (placebo)
Interventions
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methylphenidate hydrochloride
Sugar pill (placebo)
Eligibility Criteria
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Inclusion Criteria
* Healthy subjects without known disease and without any chronic pain
* Subjects without known cognitive problems, which can understand the research and its goals
* Subjects who are not taking any medications
* Subjects without hearing problems
* Subjects without attention deficit disorder (ADHD) problems
Exclusion Criteria
* Subjects taking psychotropic drugs (except Ritalin) or any analgesics
* Subjects who have any contradictions for ritalin administration
* subjects with suspected cognitive disability
20 Years
40 Years
MALE
Yes
Sponsors
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Rambam Health Care Campus
OTHER
Responsible Party
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Eisenberg Elon MD
Director, Pain research Unit
Principal Investigators
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Elon Eisenberg, MD
Role: PRINCIPAL_INVESTIGATOR
Rambam Helthcare Campus, Haifa, Israel 31096
Locations
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Rambam Healthcare Campus
Haifa, , Israel
Countries
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Other Identifiers
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Ritalin version 5
Identifier Type: OTHER
Identifier Source: secondary_id
275-13-RMB
Identifier Type: -
Identifier Source: org_study_id
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