Trial Outcomes & Findings for Congenital Sucrase-Isomaltase Deficiency (CSID) Genetic Prevalence Study (GPS) (NCT NCT01914003)

NCT ID: NCT01914003

Last Updated: 2017-11-06

Results Overview

Prevalence of CSID genetic variants in subjects 18 years of age or younger with a primary symptom of chronic idiopathic diarrhea or chronic abdominal pain without constipation.

Recruitment status

COMPLETED

Target enrollment

53 participants

Primary outcome timeframe

1 year

Results posted on

2017-11-06

Participant Flow

Participant milestones

Participant milestones
Measure
CSID Mutations
Individual has one or more known CSID mutations.
Control
Individual does not have any known CSID mutations.
Overall Study
STARTED
27
26
Overall Study
COMPLETED
19
14
Overall Study
NOT COMPLETED
8
12

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Congenital Sucrase-Isomaltase Deficiency (CSID) Genetic Prevalence Study (GPS)

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
CSID Mutations
n=27 Participants
Individual has one or more known CSID mutations.
Control
n=26 Participants
Individual does not have any known CSID mutations.
Total
n=53 Participants
Total of all reporting groups
Age, Categorical
<=18 years
27 Participants
n=5 Participants
26 Participants
n=7 Participants
53 Participants
n=5 Participants
Age, Categorical
Between 18 and 65 years
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
Age, Categorical
>=65 years
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
Age, Continuous
8 years
n=5 Participants
10.5 years
n=7 Participants
9 years
n=5 Participants
Sex: Female, Male
Female
14 Participants
n=5 Participants
16 Participants
n=7 Participants
30 Participants
n=5 Participants
Sex: Female, Male
Male
13 Participants
n=5 Participants
10 Participants
n=7 Participants
23 Participants
n=5 Participants
Region of Enrollment
United States
27 participants
n=5 Participants
26 participants
n=7 Participants
53 participants
n=5 Participants

PRIMARY outcome

Timeframe: 1 year

Prevalence of CSID genetic variants in subjects 18 years of age or younger with a primary symptom of chronic idiopathic diarrhea or chronic abdominal pain without constipation.

Outcome measures

Outcome measures
Measure
CSID Mutations
n=27 Participants
Individual has one or more known CSID mutations.
Control
n=26 Participants
Individual does not have any known CSID mutations.
Prevalence of CSID Genetic Variants
27 Participants
0 Participants

Adverse Events

CSID Mutations

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Control

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Heather Smith, Director of One Patient Services

QOL Medical, LLC

Phone: 919-832-4949

Results disclosure agreements

  • Principal investigator is a sponsor employee As outlined in each Clinical Trial Agreement between Sponsor and PI.
  • Publication restrictions are in place

Restriction type: OTHER