Long Term Study to Evaluate Safety and Efficacy of M518101 in Subjects With Plaque Psoriasis

NCT ID: NCT01908595

Last Updated: 2015-09-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

480 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-08-31

Study Completion Date

2015-05-31

Brief Summary

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This study is to evaluate the efficacy and safety for long term use of M518101 in subjects with plaque psoriasis.

Detailed Description

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Conditions

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Psoriasis

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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M518101

Proper quantity twice daily

Group Type EXPERIMENTAL

M518101

Intervention Type DRUG

Interventions

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M518101

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Who are able and willing to give signed informed consent
* Who are male or females aged 18 years or older with plaque psoriasis confirmed by the Investigator.
* Who have up to 20% of body surface area (BSA) afflicted with plaques
* Who are neither pregnant nor breast-feeding, nor plan to become pregnant during the study.

Exclusion Criteria

* Who have a history of allergy to vitamin D3 derivative preparations or a history of relevant drug hypersensitivity.
* Who are pregnant or lactating.
* Who have any renal or hepatic insufficiency, or clinically significant cardiac, renal or hepatic disease.
* Who are not deemed eligible as determined by medical history, physical examination or clinical laboratory safety tests.
* Who have clinically relevant history or presence of any disease or surgical history other than psoriasis which is likely to affect the conduct of the study.
* Whose serum calcium levels exceed the upper limit of reference range
* Who have used any investigational medicinal product and/or participated in any clinical study within 60 days of treatment.
* Who have been treated with systemic therapy within 30days of treatment.
* Who have treated with biologics within 5 half-lives of the biologics before the day of treatment
* Who have been treated with topical therapy within 14days before the day of treatment.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Maruho North America Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Agave Clinical Research

Mesa, Arizona, United States

Site Status

Bakersfield Dermatology and Skin Cancer Medical Group

Bakersfield, California, United States

Site Status

Dermatology Research Associates

Los Angeles, California, United States

Site Status

Medical Center for Clinical Research

San Diego, California, United States

Site Status

ATS Clinical Research

Santa Monica, California, United States

Site Status

Horizons Clinical Research Center

Denver, Colorado, United States

Site Status

Dermatology and Aesthetic Center Skin Care

Boca Raton, Florida, United States

Site Status

Jacksonville Center for Clinical Research

Jacksonville, Florida, United States

Site Status

FXM Research Miramar

Miramar, Florida, United States

Site Status

Renstar Medical Research

Ocala, Florida, United States

Site Status

USF Health Morsani Center for Advanced Healthcare

Tampa, Florida, United States

Site Status

Peachtree Dermatology Associates Research Center

Atlanta, Georgia, United States

Site Status

Northshore University Health System

Skokie, Illinois, United States

Site Status

South bend clinic

South Bend, Indiana, United States

Site Status

Kansas City Dermatology

Overland Park, Kansas, United States

Site Status

Minnesota Clinical Study Center

Fridley, Minnesota, United States

Site Status

J Woodson Dermatology and Associates

Henderson, Nevada, United States

Site Status

New York University

New York, New York, United States

Site Status

PMG research of raleigh

Cary, North Carolina, United States

Site Status

PMG Research of Wilmington

Wilmington, North Carolina, United States

Site Status

Radiant Research

Cincinnati, Ohio, United States

Site Status

Bager Allergy, Asthma and Dermatology Research Center

Lake Oswego, Oregon, United States

Site Status

PMG Research of Bristol

Kingsport, Tennessee, United States

Site Status

Dermatology Associates of Knoxville

Knoxville, Tennessee, United States

Site Status

The skin wellness center

Knoxville, Tennessee, United States

Site Status

Suzanne Bruce & Associates

Houston, Texas, United States

Site Status

Research Across America

Plano, Texas, United States

Site Status

Progressive Clinical Research

San Antonio, Texas, United States

Site Status

Stephen Miller

San Antonio, Texas, United States

Site Status

Dermatology Research Center

Salt Lake City, Utah, United States

Site Status

Madison Skin & Research

Madison, Wisconsin, United States

Site Status

Countries

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United States

Other Identifiers

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M518101-US04

Identifier Type: -

Identifier Source: org_study_id

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