DCs Vaccine Combined With Cytokine-induced Killer Cells in Patients With AML
NCT ID: NCT01898663
Last Updated: 2024-07-01
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
PHASE1/PHASE2
30 participants
INTERVENTIONAL
2013-06-30
2024-12-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NA
SINGLE_GROUP
TREATMENT
NONE
Study Groups
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Adenovirus-transfected DC + CIK
Adenovirus-transfected autologous DCs + CIK cells
Adenovirus-transfected DC + CIK
Adenovirus-transfected autologous DC vaccine plus CIK cells
Interventions
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Adenovirus-transfected DC + CIK
Adenovirus-transfected autologous DC vaccine plus CIK cells
Eligibility Criteria
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Inclusion Criteria
* Age≥18 years at time of consent
* KPS(Karnofsky Performance Scale) ≥70
* Patient's written informed consent
* No steroid therapy within 4 weeks of first DC vaccination
* Stable disease, complete response and partial response(WHO, RECIST)
* Predicted survival≥3 months
Exclusion Criteria
* Received organ transplantation
* Patients with other malignancies or brain metastases
* History of autoimmune diseases
* Pregnant and breast-feeding patient
* Active or chronic infectious diseases
* History of allergy or hypersensitivity to study product excipients
* Currently participating in another clinical trial
* Received chemotherapy, radiotherapy, immune inhibitor (such as corticosteroid) or other immunotherapy (such as vaccine) during prior 4 weeks
* Unfit for participating in this clinical trial in investigators' opinions
18 Years
ALL
No
Sponsors
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Affiliated Hospital to Academy of Military Medical Sciences
OTHER
Responsible Party
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Principal Investigators
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Chen Hu, M.D., Ph.D.
Role: PRINCIPAL_INVESTIGATOR
Affiliated Hospital to Academy of Military Medical Sciences
Locations
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Department of Hematopoietic Stem Cell Transplantation
Beijing, , China
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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307-CTC-DC/CIK
Identifier Type: -
Identifier Source: org_study_id
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