Efficacy and Safety of the Investigational Device, SurgiShield Anti-Adhesion Barrier Gel

NCT ID: NCT01895933

Last Updated: 2023-12-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

33 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-03-31

Study Completion Date

2013-04-30

Brief Summary

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This clinical trial is intended to evaluate the impact, efficacy, and safety of Chitosan formulated adhesion inhibitor, SurgiShield when used in the process of wound healing after endoscopic sinus surgery.

Detailed Description

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Conditions

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Wound Healing

Keywords

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Investigational device (chitosan gel) Wound healing Endoscopic sinus surgery SurgiShield

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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Active / control

One side has been treated with SurgiShield

Group Type ACTIVE_COMPARATOR

5ml surgishield

Intervention Type DEVICE

in the case of active, apply solution type adhesion barrier to merocel and pack 5ml of adhesion inhibitor Surgi Shield on the surgical site

merocel in the inflated state maintained for 36\~48 hours, remove packing then solution type adhesion inhibitor is to be injected in to the surgical site

No intervention

One side has no intervention

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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5ml surgishield

in the case of active, apply solution type adhesion barrier to merocel and pack 5ml of adhesion inhibitor Surgi Shield on the surgical site

merocel in the inflated state maintained for 36\~48 hours, remove packing then solution type adhesion inhibitor is to be injected in to the surgical site

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* older than 21 years of age
* both side sinusitis
* will undergo endoscopic sinus surgery
* volunteers with informed consent and signature

Exclusion Criteria

* suppressed immunity patient
* systemic grave condition
* pregnant
* cancer
* severe disease patients
* asthma patients
* AIDS
* cystic fibrosis
* ciliary immobility syndrome
* neutropenia neutrophil
* immunoglobulin deficiency
* wound healing immune disease
* severe liver disease
* severe kidney disease
* lymph or blood clotting disorder or patients treated with coagulants
* patients taking oral or parenteral glucose for diabetes thrombocytopenia
* infectious disease
* currently lactating
* severe septal deviation
* case where there is a severe difference in sinusitis state between sides of nose: there is a 3 or more score difference on the Lund-Mackey CT scan scoring system PNS(ParaNasalSinus)
* shellfish allergy
* food allergy
* had endoscopic sinus surgery in the past
* patient with large sinus polyps
* patients who have received treatment for extrasinus complication
Minimum Eligible Age

21 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Dankook University

OTHER

Sponsor Role collaborator

Chungbuk National University

OTHER

Sponsor Role collaborator

D.med

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Chungbook National University Hospital

Chungju, ChoongChungBukDo, South Korea

Site Status

Dankook University Hospital

Cheonan, Chungcheongnam-do, South Korea

Site Status

Countries

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South Korea

Other Identifiers

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DMED-SS001

Identifier Type: -

Identifier Source: org_study_id