Pharmacokinetic Study of Testosterone Enanthate

NCT ID: NCT01887418

Last Updated: 2018-01-11

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

View full results

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

PHASE1/PHASE2

Total Enrollment

39 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-09-30

Study Completion Date

2014-01-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Relative Bioavailability and Safety comparison of 3 formulations of Testosterone Enanthate.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Standard Pharmacokinetic (PK) analyses of data for serum testosterone were done. Cmax, Area Under Curve (AUC), and Cavg were used for the comparison of relative bioavailability of the treatments and reference arm.

Safety comparisons were based upon the occurrence, severity and rate of treatment emergent adverse events.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Hypogonadism

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

QuickShot™ - 100 mg Treatment A

QuickShot™Testosterone - Auto-injector device for SC use

Group Type EXPERIMENTAL

QuickShot™ - 100 mg Treatment A

Intervention Type DRUG

QuickShot™ for the delivery of testosterone

QuickShot™ - 50 mg Treatment B

QuickShot™Testosterone- Auto-injector device for SC use

Group Type EXPERIMENTAL

QuickShot™ - 50 mg Treatment B

Intervention Type DRUG

QuickShot™ for the delivery of testosterone

Delatestryl 200 mg IM Treatment C

Commercially available Testosterone enanthate 200 mg IM dosage - 'standard of care' arm for reference

Group Type ACTIVE_COMPARATOR

Delatestryl 200 mg IM Treatment C

Intervention Type DRUG

Standard of care

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

QuickShot™ - 50 mg Treatment B

QuickShot™ for the delivery of testosterone

Intervention Type DRUG

QuickShot™ - 100 mg Treatment A

QuickShot™ for the delivery of testosterone

Intervention Type DRUG

Delatestryl 200 mg IM Treatment C

Standard of care

Intervention Type DRUG

Other Intervention Names

Discover alternative or legacy names that may be used to describe the listed interventions across different sources.

Testosterone Testosterone enanthate Testosterone Testosterone enanthate Testosterone Testosterone enanthate

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Adult males aged 18 to 75 with a documented diagnosis of hypogonadism

Exclusion Criteria

* Normal testosterone levels
* Subjects with any clinically significant medical condition which, in the opinion of the Investigator, would make the subject an unsuitable candidate for enrollment in the study
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Antares Pharma Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Gary Bedel, MD

Role: PRINCIPAL_INVESTIGATOR

Prestige Clinical Research

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Mens Health Boston

Brookline, Massachusetts, United States

Site Status

Countries

Review the countries where the study has at least one active or historical site.

United States

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

QST-13-002

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

ORAL T-6: Oral Androgens in Man-6
NCT00663793 COMPLETED PHASE1
Oral T7 Oral Testosterone in Man
NCT00842751 COMPLETED PHASE2