Effects of Exercise Training on Mechanoreflex and Metaboreflex Control in Heart Failure Patients

NCT ID: NCT01884142

Last Updated: 2021-04-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

34 participants

Study Classification

INTERVENTIONAL

Study Start Date

2008-03-31

Study Completion Date

2014-01-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The investigators hypothesize that exercise training would improve the mechanoreflex and metaboreflex control in heart failure patients.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Heart Failure

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Heart Failure Untrained Group

Control Group

Group Type NO_INTERVENTION

No interventions assigned to this group

Heart Failure Exercise-trained Group

Aerobic Exercise Training

Group Type EXPERIMENTAL

Aerobic Exercise Training

Intervention Type OTHER

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Aerobic Exercise Training

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Patients with systolic heart failure;
* New York Heart Association (NYHA) class II-III;
* Left ventricular ejection fraction less than 40%;
* Peak Oxygen Consumption less than 20 ml/Kg/min;
* Stable Clinical Status.

Exclusion Criteria

* Chronic Obstructive Pulmonary Disease;
* Neuromuscular Diseases;
* Orthopedic Diseases;
* Neurologic Diseases;
* Neoplastic Diseases;
* Recent myocardial infarction or cardiac surgery (less than 6 months);
* Unstable angina pectoris;
* Atrial Fibrillation;
* Pacemakers users;
* Changing medication or hospital admission.
Minimum Eligible Age

30 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Fundação de Amparo à Pesquisa do Estado de São Paulo

OTHER_GOV

Sponsor Role collaborator

Conselho Nacional de Desenvolvimento Científico e Tecnológico

OTHER_GOV

Sponsor Role collaborator

University of Sao Paulo General Hospital

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Lígia M. Antunes-Correa

PhD student

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Carlos E Negrão, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Sao Paulo General Hospital

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Heart Institute (InCor), University of Sao Paulo Medical School

São Paulo, , Brazil

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Brazil

References

Explore related publications, articles, or registry entries linked to this study.

Unable to connect to PubMed to validate , last attempt on June 19, 2013 at 12:03 PM EDT

Reference Type BACKGROUND

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

Ergoreflex

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.