Trial Outcomes & Findings for Acupuncture in Reducing the Severity of Chemoradiation-induced Mucositis in Patients With Oropharyngeal Cancer (NCT NCT01883908)

NCT ID: NCT01883908

Last Updated: 2019-11-07

Results Overview

All acupuncture side effects will be recorded

Recruitment status

TERMINATED

Study phase

NA

Target enrollment

4 participants

Primary outcome timeframe

16 weeks

Results posted on

2019-11-07

Participant Flow

University Medical Centers and Hospital Based Oncology Programs recruited participants from January 2013 until June 2014.

Four participants were enrolled, with three randomized to receive acupuncture and one randomized to receive standard medical care.

Participant milestones

Participant milestones
Measure
Acupuncture With Seirin® Needles
Participants will be randomized to receive acupuncture treatment plus usual medical care once a week for 8 weeks coinciding with their chemoradiation treatments. The length of the study will be 16 weeks: 8 weeks of treatment and two follow up visits at 4 weeks and 8 weeks after radiation (weeks 12 and 16). Acupuncture with Seirin® needles: Participants will be randomized to receive either usual medical care or acupuncture treatment plus usual medical care once a week for 8 weeks coinciding with their chemoradiation treatments. The length of the study will be 16 weeks: 8 weeks of treatment and two follow up visits at 4 weeks and 8 weeks after radiation (weeks 12 and 16). Usual medical care: usual medical care such as viscous Lidocaine for relief of pain
Usual Medical Care
Participants will be randomized to receive usual medical care for 8 weeks coinciding with their chemoradiation treatments. Patients will receive usual medical care such as viscous Lidocaine for relief of pain. Usual medical care: usual medical care such as viscous Lidocaine for relief of pain
Overall Study
STARTED
3
1
Overall Study
COMPLETED
3
1
Overall Study
NOT COMPLETED
0
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Acupuncture in Reducing the Severity of Chemoradiation-induced Mucositis in Patients With Oropharyngeal Cancer

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Acupuncture With Seirin® Needles
n=3 Participants
Participants will be randomized to receive acupuncture treatment plus usual medical care once a week for 8 weeks coinciding with their chemoradiation treatments. The length of the study will be 16 weeks: 8 weeks of treatment and two follow up visits at 4 weeks and 8 weeks after radiation (weeks 12 and 16). Acupuncture with Seirin® needles: Participants will be randomized to receive either usual medical care or acupuncture treatment plus usual medical care once a week for 8 weeks coinciding with their chemoradiation treatments. The length of the study will be 16 weeks: 8 weeks of treatment and two follow up visits at 4 weeks and 8 weeks after radiation (weeks 12 and 16). Usual medical care: usual medical care such as viscous Lidocaine for relief of pain
Usual Medical Care
n=1 Participants
Participants will be randomized to receive usual medical care for 8 weeks coinciding with their chemoradiation treatments. Patients will receive usual medical care such as viscous Lidocaine for relief of pain. Usual medical care: usual medical care such as viscous Lidocaine for relief of pain
Total
n=4 Participants
Total of all reporting groups
Age, Customized
63 years
n=5 Participants
55 years
n=7 Participants
63 years
n=5 Participants
Sex: Female, Male
Female
1 Participants
n=5 Participants
0 Participants
n=7 Participants
1 Participants
n=5 Participants
Sex: Female, Male
Male
2 Participants
n=5 Participants
1 Participants
n=7 Participants
3 Participants
n=5 Participants
Region of Enrollment
United States
3 participants
n=5 Participants
1 participants
n=7 Participants
4 participants
n=5 Participants

PRIMARY outcome

Timeframe: 16 weeks

Population: Zero participants analyzed due to early termination of study.

All acupuncture side effects will be recorded

Outcome measures

Outcome data not reported

PRIMARY outcome

Timeframe: 16 weeks

Population: Zero participants analyzed due to early termination of study.

Feasibility is defined as greater than 80% patients in the trial completing at least 4 acupuncture sessions.

Outcome measures

Outcome data not reported

Adverse Events

Acupuncture With Seirin® Needles

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Usual Medical Care

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Michelle Medeiros

University of Maryland Baltimore Greenebaum Cancer Center

Phone: 410-328-1160

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place