Study of Opioid Immunosuppressive Effects

NCT ID: NCT01881802

Last Updated: 2013-06-20

Basic Information

• Recruitment Status: UNKNOWN
• Total Enrollment: 50 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2013-03-31

Brief Summary

This trial aims to investigate the effects of opioid-inducing immune suppression on opioid drug abused patients. The methods of the investigators research mainly includes the expression of morphine-related miRNAs in peripheral blood mononuclear cells and cytokine in plasma.

Conditions

Opioid Abuse or Dependence

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: CROSS_SECTIONAL

Study Groups

morphine or heroin dependence patients

No interventions assigned to this group

normal control group

No interventions assigned to this group

Eligibility Criteria

Inclusion Criteria

• subjects were excluded if they had a chronic systemic illness (cardiac, renal, pulmonary, hepatic, endocrine, metabolic, or autoimmune disorders) or
• a major psychiatric disorder or
• if they were abusing substances other than heroin (as determined by urine drug test result). For women, pregnancy was also a reason for exclusion.

Exclusion Criteria

• Control subjects with no history of drug or alcohol abuse were also excluded if they had
• major medical or psychiatric disorders

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 55 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

OTHER

Sponsor Role: lead

Responsible Party

Xiaohong Long

doctoral candidate

Responsibility Role: PRINCIPAL_INVESTIGATOR

Other Identifiers

01

Identifier Type: -

Identifier Source: org_study_id