Plasma Vitamin and Homocysteine Levels and Thrombosis in Patients With Ph-negative MPNs

NCT ID: NCT01878916

Last Updated: 2013-06-17

Basic Information

• Recruitment Status: COMPLETED
• Study Classification: OBSERVATIONAL
• Study Start Date: 2003-01-31
• Study Completion Date: 2004-06-30

Brief Summary

Hyperhomocysteinemia is a risk for thrombosis. Thrombosis is more frequent in myeloproliferative neoplasms (MPNs) than the normal population. In this study, we investigated the thrombosis incidence, the effects of plasma homocysteine levels on thrombosis, and the correlations between folate, cobalamin, pyridoxine and homocysteine levels in MPNs, and to compare these results with the healthy controls.

Detailed Description

Thirty-one new or formerly diagnosed MPN patients who consecutively visitted our outpatient clinic, as well as 40 age and sex matched healthy controls were enrolled in this study.

Conditions

Thrombosis

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Eligibility Criteria

Inclusion Criteria

Adult MPN patients and healthy controls who gave a written consent were included in the study.

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Istanbul University

OTHER

Sponsor Role: lead

Responsible Party

Dr. A. Emre Eşkazan

MD

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Ahmet Emre Eskazan, MD

Role: PRINCIPAL_INVESTIGATOR

Istanbul University

Locations

Istanbul University Cerrahpasa Medical Faculty

Istanbul, , Turkey (Türkiye)

Countries

Turkey (Türkiye)

Other Identifiers

HcyMPN

Identifier Type: -

Identifier Source: org_study_id