Trial Outcomes & Findings for Promoting Smoking Cessation in Carpenters (NCT NCT01878214)

NCT ID: NCT01878214

Last Updated: 2014-12-04

Results Overview

Enrollment records from the union-sponsored smoking cessation program

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

442 participants

Primary outcome timeframe

up to 12 months after recruitment

Results posted on

2014-12-04

Participant Flow

We invited 1937 union members to participate; 1638 members completed the baseline survey (84.6%). Of those, 553 were current smokers, 1066 were non-smokers, and the smoking status was unknown for 19 individuals. The smoking rate was 33.8%, slightly lower than expected based on previous studies in this population.

Of 553 current smokers, 111 were not eligible for study inclusion because they either did not sign a consent form (n=49), were not eligible for union benefits (n=57), or had too much data missing at baseline (n=5). The 442 eligible smokers were separated into the four segments and then randomized into the intervention group or the control group.

Participant milestones

Participant milestones
Measure
Intervention Group
Targeted messaging Targeted messaging: 1 informational letter plus 6 targeted mailed messages and 6 booster text messages Standard messaging: 1 informational letter
Control Group
Standard messaging Standard messaging: 1 informational letter
Overall Study
STARTED
223
219
Overall Study
COMPLETED
170
175
Overall Study
NOT COMPLETED
53
44

Reasons for withdrawal

Reasons for withdrawal
Measure
Intervention Group
Targeted messaging Targeted messaging: 1 informational letter plus 6 targeted mailed messages and 6 booster text messages Standard messaging: 1 informational letter
Control Group
Standard messaging Standard messaging: 1 informational letter
Overall Study
Withdrawal by Subject
18
7
Overall Study
Death
0
1
Overall Study
Lost to Follow-up
35
36

Baseline Characteristics

Promoting Smoking Cessation in Carpenters

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Intervention Group
n=223 Participants
Targeted messaging Targeted messaging: 1 informational letter plus 6 targeted mailed messages and 6 booster text messages Standard messaging: 1 informational letter
Control Group
n=219 Participants
Standard messaging Standard messaging: 1 informational letter
Total
n=442 Participants
Total of all reporting groups
Age, Continuous
35.64 years
STANDARD_DEVIATION 11.54 • n=5 Participants
35.18 years
STANDARD_DEVIATION 11.54 • n=7 Participants
35.33 years
STANDARD_DEVIATION 11.44 • n=5 Participants
Age, Categorical
<=18 years
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
Age, Categorical
Between 18 and 65 years
221 Participants
n=5 Participants
218 Participants
n=7 Participants
439 Participants
n=5 Participants
Age, Categorical
>=65 years
2 Participants
n=5 Participants
1 Participants
n=7 Participants
3 Participants
n=5 Participants
Sex: Female, Male
Female
3 Participants
n=5 Participants
1 Participants
n=7 Participants
4 Participants
n=5 Participants
Sex: Female, Male
Male
220 Participants
n=5 Participants
218 Participants
n=7 Participants
438 Participants
n=5 Participants
Region of Enrollment
United States
223 participants
n=5 Participants
219 participants
n=7 Participants
442 participants
n=5 Participants

PRIMARY outcome

Timeframe: up to 12 months after recruitment

Population: Includes all study subjects

Enrollment records from the union-sponsored smoking cessation program

Outcome measures

Outcome measures
Measure
Intervention Group
n=223 Participants
Targeted messaging Targeted messaging: 6 targeted mailed messages and 6 booster text messages Standard messaging: 1 informational letter
Control Group
n=219 Participants
Standard messaging Standard messaging: 1 informational letter
Enrollment in Smoking Cessation Program
5 participants
4 participants

SECONDARY outcome

Timeframe: 7 months after baseline

Population: Secondary outcomes were collected via self-report survey approximately 7 months after study enrollment; 345 subjects (78%) completed the follow-up survey.

At follow-up, subjects will report current smoking status. ("Do you currently smoke (have you smoked in the last 30 days)?" \[Yes, I smoked within the past 30 days; No, but I have smoked in the past 6 months; No, and I have not smoked in more than 6 months\]). We will report the % of subjects who have not smoked in the last 30 days and will compare the intervention group with the control group.

Outcome measures

Outcome measures
Measure
Intervention Group
n=170 Participants
Targeted messaging Targeted messaging: 6 targeted mailed messages and 6 booster text messages Standard messaging: 1 informational letter
Control Group
n=175 Participants
Standard messaging Standard messaging: 1 informational letter
Quit Smoking
17.1 percentage of participants
16.0 percentage of participants

SECONDARY outcome

Timeframe: 7 months after recruitment

Population: Secondary outcomes were collected via self-report survey approximately 7 months after study enrollment; 345 subjects (78%) completed the follow-up survey. This outcome was only measured in those who reported smoking in the last 30 days (n=288, 83.5%).

At baseline and follow-up, subjects will report smoking frequency ("How often do you smoke?" \[everyday, at least 4 days/week, 1-3 days/week, less than one day/week\]) and quantity ("On days that you smoke, how many cigarettes do you have per day?" \[10 or less, 11-20, 21-30, 31 or more\]). We will report the % of subjects who smoke less frequently and smoke fewer cigarettes per day at follow-up compared to baseline. We will compare the intervention group with the control group.

Outcome measures

Outcome measures
Measure
Intervention Group
n=141 Participants
Targeted messaging Targeted messaging: 6 targeted mailed messages and 6 booster text messages Standard messaging: 1 informational letter
Control Group
n=147 Participants
Standard messaging Standard messaging: 1 informational letter
Changes in Smoking Behaviors (Frequency and Quantity)
Smoked fewer cigarettes per day
24.8 percentage of participants
19.7 percentage of participants
Changes in Smoking Behaviors (Frequency and Quantity)
Smoked less frequently
14.8 percentage of participants
12.2 percentage of participants

SECONDARY outcome

Timeframe: 7 months after recruitment

Population: Secondary outcomes were collected via self-report survey approximately 7 months after study enrollment; 345 subjects (78%) completed the follow-up survey. This outcome was only measured in those who reported smoking in the last 30 days (n=288, 83.5%).

Subjects will answer the following question at both baseline and follow-up surveys: "Are you seriously considering quitting smoking in the next 6 months?" \[yes/no\]. We will report % of subjects who said "no" at baseline and "yes" at follow-up to determine changes in readiness to quit smoking and compare between intervention and control groups.

Outcome measures

Outcome measures
Measure
Intervention Group
n=141 Participants
Targeted messaging Targeted messaging: 6 targeted mailed messages and 6 booster text messages Standard messaging: 1 informational letter
Control Group
n=147 Participants
Standard messaging Standard messaging: 1 informational letter
Changes in Readiness to Quit Smoking in the Next 6 Months
9.2 percentage of participants
13.6 percentage of participants

SECONDARY outcome

Timeframe: 7 months after recruitment

Population: Secondary outcomes were collected via self-report survey approximately 7 months after study enrollment; 345 subjects (78%) completed the follow-up survey. This outcome was only measured in those who reported smoking in the last 30 days (n=288, 83.5%).

At baseline and follow-up, subjects will answer questions about motivation to quit smoking ("How motivated are you to quit smoking at this time? \[scale: 1 (not at all) - 10 (extremely)\]) and thinking about quitting smoking ("Each rung on this ladder represents where various smokers are in their thinking about quitting. Circle the number that indicates where you are now. \[0 (no thoughts of quitting) -10 (taking action to quit)\]). We will report the % of subjects who reported more motivation to quit and greater thinking about quitting at follow-up compared to baseline. We will compare the intervention group with the control group.

Outcome measures

Outcome measures
Measure
Intervention Group
n=141 Participants
Targeted messaging Targeted messaging: 6 targeted mailed messages and 6 booster text messages Standard messaging: 1 informational letter
Control Group
n=147 Participants
Standard messaging Standard messaging: 1 informational letter
Changes in Motivation to Quit Smoking and Thinking About Quitting Smoking
More motivated to quit smoking
14.9 percentage of participants
23.8 percentage of participants
Changes in Motivation to Quit Smoking and Thinking About Quitting Smoking
Greater thinking about quitting smoking
12.1 percentage of participants
22.5 percentage of participants

Adverse Events

Intervention Group

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Control Group

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Jaime Strickland, MA

Washington University School of Medicine in St. Louis

Phone: 314-454-7337

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place