Samsung Medical Center-Lymphoma Cohort Study-II

NCT ID: NCT01877109

Last Updated: 2017-10-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

1358 participants

Study Classification

OBSERVATIONAL

Study Start Date

2012-02-01

Study Completion Date

2017-02-28

Brief Summary

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The purpose of this study is to establish a model which can predict the treatment outcome and the risk of treatment-related morbidity in patients with lymphoma.

Detailed Description

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Although the cure rate of lymphoma has been increased due to the development of newer effective drugs, a substantial portion of patients is still suffered from relapse. Furthermore, the treatment-related morbidity is another factor which can make the treatment outcome worse in patients with lymphoma, especially elderly patients. Thus, this study is going to assess factors which may affect the treatment outcome and the risk of treatment-related morbidity.

1.Biologic factors associated with the aggressiveness of lymphoma

* molecular markers in serum, cytogenetic markers 2.Factors associated with the risk of treatment-related morbidity
* comorbidity, nutrition status, performance status, quality of life at diagnosis

Conditions

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Lymphoma

Keywords

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Lymphoma Prognosis Biomarker Quality of life

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Lymphoma

Lymphoma patients

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Patients who were diagnosed as lymphoma
* Over 19 years old
* Patients who agreed the enrollment of study
* Informed consent for sampling

Exclusion Criteria

•Patients who do not want to join the study
Minimum Eligible Age

19 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Samsung Medical Center

OTHER

Sponsor Role lead

Responsible Party

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Won Seog Kim

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Samsung Medical Center

Seoul, , South Korea

Site Status

Countries

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South Korea

References

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Cho I, Lee H, Yoon SE, Ryu KJ, Ko YH, Kim WS, Kim SJ. Serum levels of soluble programmed death-ligand 1 (sPD-L1) in patients with primary central nervous system diffuse large B-cell lymphoma. BMC Cancer. 2020 Feb 13;20(1):120. doi: 10.1186/s12885-020-6612-2.

Reference Type DERIVED
PMID: 32054467 (View on PubMed)

Kim SJ, Hong M, Do IG, Lee SH, Ryu KJ, Yoo HY, Hong JY, Ko YH, Kim WS. Serum survivin and vascular endothelial growth factor in extranodal NK/T-cell lymphoma, nasal type: implications for a potential new prognostic indicator. Haematologica. 2015 Mar;100(3):e106-9. doi: 10.3324/haematol.2014.116087. Epub 2014 Dec 5. No abstract available.

Reference Type DERIVED
PMID: 25480498 (View on PubMed)

Other Identifiers

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2011-11-056

Identifier Type: -

Identifier Source: org_study_id