TARGet Kids!: Measuring Nutrition in Young Preschool Children in the Primary Care Practice Setting

NCT ID: NCT01869530

Last Updated: 2021-11-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

14000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2008-07-31

Study Completion Date

2030-06-30

Brief Summary

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TARGet Kids! (The Applied Research Group for Kids) is a research study enrolling healthy children aged 0-5 years. The aim of the TARGet Kids! registry is to link early life exposures to health problems including obesity, micronutrient deficiencies, and developmental problems.

TARGet Kids! represents an innovative collaboration between child health researchers and children's primary care doctors (pediatricians and family physicians) to promote research that really matters and create solutions to some of the today's biggest health concerns. The results of this collaborative research study are not only improving the quality of children's healthcare but also the health of children across the country. Coordinated by Sick Kids and St. Michael's Hospital with data management services by the Applied Health Research Centre (AHRC), TARGet Kids! is the only primary care research network for children in Canada.

Detailed Description

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Conditions

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Nutritional Disorders Obesity Development

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Healthy children

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Birth to less than 6 years of age
* Parental consent
* Attending a TARGet Kids! research network practice

Exclusion Criteria

* Chronic illness with the exception of asthma
Maximum Eligible Age

5 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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The Hospital for Sick Children

OTHER

Sponsor Role lead

Responsible Party

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Catherine Birken

Staff Paediatrician

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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St. Michael's Hospital

Toronto, Ontario, Canada

Site Status RECRUITING

Hospital for Sick Children

Toronto, Ontario, Canada

Site Status RECRUITING

Melville Pediatric Center

Montreal, Quebec, Canada

Site Status RECRUITING

Countries

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Canada

Central Contacts

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Catherine Birken, MD, M.Sc., FRCPC

Role: CONTACT

Phone: 416-813-7654

Email: [email protected]

Dalah Mason, MPH

Role: CONTACT

Phone: 416-813-7654

Email: [email protected]

Facility Contacts

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Jonathon Maguire, MD, MSc, FRCPC

Role: primary

Catherine Birken, MD, M.Sc., FRCPC

Role: primary

Dalah Mason, MPH

Role: backup

Patricia Li, MD

Role: primary

Elise Mok, MD

Role: backup

References

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Borkhoff CM, Imsirovic H, Bayoumi I, Macarthur C, Nurse KM, To T, Feldman M, Lau E, Knight B, Birken CS, Maguire JL, Parkin PC. Developmental screening at 18 months using the Nipissing District Developmental Screen. Paediatr Child Health. 2025 May 11;30(6):477-485. doi: 10.1093/pch/pxaf023. eCollection 2025 Sep.

Reference Type DERIVED
PMID: 41049705 (View on PubMed)

Kucab MD, Keown-Stoneman CD, Birken CS, Perlman M, Parsons J, D'Annunzio D, Thadani S, Allen CA, Maguire JL; TARGet Kids! Collaboration. Center-Based Childcare in Early Childhood and Nutritional Risk in Later Childhood: A Prospective Cohort Study. J Nutr. 2025 Sep 27:S0022-3166(25)00573-5. doi: 10.1016/j.tjnut.2025.09.028. Online ahead of print.

Reference Type DERIVED
PMID: 41022151 (View on PubMed)

Nurse KM, Parkin PC, Keown-Stoneman CDG, Bayoumi I, Birken CS, Maguire JL, Macarthur C, Borkhoff CM. Association Between Family Income and Positive Developmental Screening Using the Infant Toddler Checklist at the 18-Month Health Supervision Visit. J Pediatr. 2024 Jan;264:113769. doi: 10.1016/j.jpeds.2023.113769. Epub 2023 Nov 1.

Reference Type DERIVED
PMID: 37821023 (View on PubMed)

Palumbo AM, Kirkwood D, Borkhoff CM, Keown-Stoneman CDG, Muraca GM, Fuller A, Birken CS, Maguire JL, Brown HK, Anderson LN; TARGet Kids! Collaboration. Validation of Parent-reported Gestational Age Categories for Children Less Than 6 Years of Age. Epidemiology. 2023 Nov 1;34(6):767-773. doi: 10.1097/EDE.0000000000001645. Epub 2023 Sep 26.

Reference Type DERIVED
PMID: 37757868 (View on PubMed)

Braddon KE, Keown-Stoneman CD, Dennis CL, Li X, Maguire JL, O'Connor DL, Omand JA, Simpson JR, Birken CS. Maternal Preconception Body Mass Index and Early Childhood Nutritional Risk. J Nutr. 2023 Aug;153(8):2421-2431. doi: 10.1016/j.tjnut.2023.06.022. Epub 2023 Jun 24.

Reference Type DERIVED
PMID: 37356500 (View on PubMed)

Kucab MD, Keown-Stoneman CDG, Birken CS, Perlman M, Maguire JL; TARGet Kids! Collaboration. Centre-based childcare in early childhood and growth in later childhood: a prospective cohort study. Int J Obes (Lond). 2023 Aug;47(8):724-731. doi: 10.1038/s41366-023-01316-2. Epub 2023 Apr 27.

Reference Type DERIVED
PMID: 37106078 (View on PubMed)

Omand JA, Li X, Keown-Stoneman CDG, Borkhoff CM, Duku E, Lebovic G, Maguire JL, Mamdani MM, Parkin PC, Reid-Westoby C, Randall Simpson J, Tremblay MS, Janus M, Birken CS; TARGet Kids! Study Group. Body Weight at Age Four Years and Readiness to Start School: A Prospective Cohort Study. Child Obes. 2023 Jun;19(4):267-281. doi: 10.1089/chi.2022.0018. Epub 2022 Jul 13.

Reference Type DERIVED
PMID: 35834646 (View on PubMed)

Omand JA, Janus M, Maguire JL, Parkin PC, Aglipay M, Randall Simpson J, Keown-Stoneman CDG, Duku E, Reid-Westoby C, Birken CS. Nutritional Risk in Early Childhood and School Readiness. J Nutr. 2021 Dec 3;151(12):3811-3819. doi: 10.1093/jn/nxab307.

Reference Type DERIVED
PMID: 34587245 (View on PubMed)

Hamid JS, Atenafu EG, Borkhoff CM, Birken CS, Maguire JL, Bohn MK, Adeli K, Abdelhaleem M, Parkin PC. Reference intervals for hemoglobin and mean corpuscular volume in an ethnically diverse community sample of Canadian children 2 to 36 months. BMC Pediatr. 2021 May 19;21(1):241. doi: 10.1186/s12887-021-02709-w.

Reference Type DERIVED
PMID: 34011305 (View on PubMed)

Bayoumi I, Birken CS, Nurse KM, Parkin PC, Maguire JL, Macarthur C, Randall Simpson JA, Borkhoff CM. Screening for marginal food security in young children in primary care. BMC Pediatr. 2021 Apr 23;21(1):196. doi: 10.1186/s12887-021-02674-4.

Reference Type DERIVED
PMID: 33892660 (View on PubMed)

Gunaseelan V, Parkin PC, Wahi G, Birken CS, Maguire JL, Macarthur C, Borkhoff CM; Members of the TARGet Kids! Collaboration. Maternal ethnicity and iron status in early childhood in Toronto, Canada: a cross-sectional study. BMJ Paediatr Open. 2020 Apr 6;4(1):e000635. doi: 10.1136/bmjpo-2020-000635. eCollection 2020.

Reference Type DERIVED
PMID: 32509978 (View on PubMed)

Birken CS, Omand JA, Nurse KM, Borkhoff CM, Koroshegyi C, Lebovic G, Maguire JL, Mamdani M, Parkin PC, Randall Simpson J, Tremblay MS, Duku E, Reid-Westoby C, Janus M; TARGet Kids! Collaboration. Fit for School Study protocol: early child growth, health behaviours, nutrition, cardiometabolic risk and developmental determinants of a child's school readiness, a prospective cohort. BMJ Open. 2019 Nov 19;9(11):e030709. doi: 10.1136/bmjopen-2019-030709.

Reference Type DERIVED
PMID: 31748293 (View on PubMed)

Parkin PC, Koroshegyi C, Mamak E, Borkhoff CM, Birken CS, Maguire JL, Thorpe KE; TARGet Kids! Collaboration. Association between Serum Ferritin and Cognitive Function in Early Childhood. J Pediatr. 2020 Feb;217:189-191.e2. doi: 10.1016/j.jpeds.2019.09.051. Epub 2019 Nov 2.

Reference Type DERIVED
PMID: 31685227 (View on PubMed)

Wong VCH, Maguire JL, Omand JA, Dai DWH, Lebovic G, Parkin PC, O'Connor DL, Birken CS; TARGet Kids! Collaboration. A Positive Association Between Dietary Intake of Higher Cow's Milk-Fat Percentage and Non-High-Density Lipoprotein Cholesterol in Young Children. J Pediatr. 2019 Aug;211:105-111.e2. doi: 10.1016/j.jpeds.2019.03.047. Epub 2019 May 17.

Reference Type DERIVED
PMID: 31104850 (View on PubMed)

Sypes EE, Parkin PC, Birken CS, Carsley S, MacArthur C, Maguire JL, Borkhoff CM; TARGet Kids! Collaboration. Higher Body Mass Index Is Associated with Iron Deficiency in Children 1 to 3 Years of Age. J Pediatr. 2019 Apr;207:198-204.e1. doi: 10.1016/j.jpeds.2018.11.035. Epub 2019 Jan 7.

Reference Type DERIVED
PMID: 30630632 (View on PubMed)

Oatley H, Borkhoff CM, Chen S, Macarthur C, Persaud N, Birken CS, Maguire JL, Parkin PC; TARGet Kids! Collaboration. Screening for Iron Deficiency in Early Childhood Using Serum Ferritin in the Primary Care Setting. Pediatrics. 2018 Dec;142(6):e20182095. doi: 10.1542/peds.2018-2095.

Reference Type DERIVED
PMID: 30487142 (View on PubMed)

Borkhoff CM, Dai DWH, Jairam JA, Wong PD, Cox KA, Maguire JL, Birken CS, Macarthur C, Parkin PC; TARGet Kids! Collaboration. Breastfeeding to 12 mo and beyond: nutrition outcomes at 3 to 5 y of age. Am J Clin Nutr. 2018 Aug 1;108(2):354-362. doi: 10.1093/ajcn/nqy124.

Reference Type DERIVED
PMID: 30101330 (View on PubMed)

Eny KM, Chen S, Anderson LN, Chen Y, Lebovic G, Pullenayegum E, Parkin PC, Maguire JL, Birken CS; TARGet Kids! Collaboration. Breastfeeding duration, maternal body mass index, and birth weight are associated with differences in body mass index growth trajectories in early childhood. Am J Clin Nutr. 2018 Apr 1;107(4):584-592. doi: 10.1093/ajcn/nqx081.

Reference Type DERIVED
PMID: 29635496 (View on PubMed)

Anderson LN, Carsley S, Lebovic G, Borkhoff CM, Maguire JL, Parkin PC, Birken CS. Misclassification of child body mass index from cut-points defined by rounded percentiles instead of Z-scores. BMC Res Notes. 2017 Nov 28;10(1):639. doi: 10.1186/s13104-017-2983-0.

Reference Type DERIVED
PMID: 29183360 (View on PubMed)

Vanderhout SM, Birken CS, Parkin PC, Lebovic G, Chen Y, O'Connor DL, Maguire JL; TARGet Kids! Collaboration. Relation between milk-fat percentage, vitamin D, and BMI z score in early childhood. Am J Clin Nutr. 2016 Dec;104(6):1657-1664. doi: 10.3945/ajcn.116.139675. Epub 2016 Nov 16.

Reference Type DERIVED
PMID: 27852618 (View on PubMed)

Related Links

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http://targetkids.ca

TARGet Kids! website

Other Identifiers

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2063

Identifier Type: -

Identifier Source: org_study_id