Lutonix Global SFA Registry

NCT ID: NCT01864278

Last Updated: 2016-11-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

691 participants

Study Classification

OBSERVATIONAL

Study Start Date

2012-12-31

Study Completion Date

2016-09-30

Brief Summary

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The registry will enroll patients with claudication or ischemic rest pain and an angiographically significant lesion in the superficial femoral or popliteal artery. Subjects will be treated with the LUTONIX Drug Coated PTA Dilatation Catheter carrying the CE Mark per current Instructions for Use(IFU) and followed clinically for a minimum of 2 years.

Detailed Description

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Conditions

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Peripheral Artery Disease

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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Lutonix Drug Coated Balloon

Paclitaxel coated ballooncatheter

Lutonix Drug Coated Balloon

Intervention Type DEVICE

Subject will receive treatment with the Lutonix Drug Coated Balloon

Interventions

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Lutonix Drug Coated Balloon

Subject will receive treatment with the Lutonix Drug Coated Balloon

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Male or non-pregnant female ≥18 years of age;
* Rutherford Clinical Category ≤ 4;
* Patient is willing to provide 5-year informed consent and comply with the required follow up;
* Stenotic or obstructive vascular lesions of the femoropopliteal artery;
* Lesion(s) can be treated with available LUTONIX Drug Coated PTA Dilatation Catheter device size matrix per current IFU;
* At least one patent native outflow artery to the ankle free from significant lesion (≥50% stenosis) as confirmed by angiography (treatment of outflow disease is NOT permitted; treatment of in-flow disease is permitted prior to treatment with the LUTONIX Drug Coated PTA Dilatation Catheter).

Exclusion Criteria

* Patient is currently participating in an investigational drug or device study;
* Inability to take recommended medications as stated in the IFU or non-controllable allergy to contrast;
* Pregnant or planning on becoming pregnant or men intending to father a child;
* Rutherford Class \> 4
* Known inadequate distal outflow or planned future treatment of vascular disease distal to the target lesion
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Bard Ltd

INDUSTRY

Sponsor Role collaborator

C. R. Bard

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Allgemeines Krankenhaus Wien

Vienna, , Austria

Site Status

ZNA Campus Middelheim

Antwerp, , Belgium

Site Status

CHU Le Bocage

Dijon, , France

Site Status

Karolinen Hospital Huesten

Arnsberg, , Germany

Site Status

Diakoniewerk Muenchen

München, , Germany

Site Status

Medinos Kliniken Sonneberg

Sonneberg, , Germany

Site Status

Kreiskrankenhaus Viechtach

Viechtach, , Germany

Site Status

Klinikum Weiden

Weiden, , Germany

Site Status

University General Hospital of Patras

Pátrai, , Greece

Site Status

AO Cardinal Massaia

Asti, , Italy

Site Status

IRCCS Policlinico San Donato

San Donato Milanese, , Italy

Site Status

Azienda Ospedaliera della Valtellina e dalla Valchiavenna

Sondalo, , Italy

Site Status

AO Ordine Mauriziano

Torino, , Italy

Site Status

Szpital Uniwersytecki nr 2 im. Biziel

Bydgoszcz, , Poland

Site Status

Szpital Kliniczny Przemienienia Panskiego

Poznan, , Poland

Site Status

Voivodship Specialist Hospital

Torun, , Poland

Site Status

Hospital Clinico Barcelona

Barcelona, , Spain

Site Status

Kantonsspital Aarau

Aarau, , Switzerland

Site Status

Royal Liverpool

Liverpool, , United Kingdom

Site Status

St Thomas' Hospital

London, , United Kingdom

Site Status

Manchester Royal Infirmary

Manchester, , United Kingdom

Site Status

Wythenshawe Hospital

Manchester, , United Kingdom

Site Status

Freeman Hospital

Newcastle upon Tyne, , United Kingdom

Site Status

Countries

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Netherlands Austria Belgium France Germany Greece Italy Poland Spain Switzerland United Kingdom

References

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Thieme M, Von Bilderling P, Paetzel C, Karnabatidis D, Perez Delgado J, Lichtenberg M; Lutonix Global SFA Registry Investigators. The 24-Month Results of the Lutonix Global SFA Registry: Worldwide Experience With Lutonix Drug-Coated Balloon. JACC Cardiovasc Interv. 2017 Aug 28;10(16):1682-1690. doi: 10.1016/j.jcin.2017.04.041. Epub 2017 Aug 2.

Reference Type DERIVED
PMID: 28780030 (View on PubMed)

Other Identifiers

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CL0004-01

Identifier Type: -

Identifier Source: org_study_id