The Aim of This Investigation is to Compare the Influence of 0.9% Saline and Plasmalyte Solution on Acid-base Balance and Electrolytes in Healthy Patients Undergoing Major Spine Surgeries.
NCT ID: NCT01855542
Last Updated: 2013-05-16
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
50 participants
INTERVENTIONAL
2012-03-31
2013-01-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
SINGLE
Study Groups
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0.9% saline
In each group, patients received either 0.9% normal saline or plasmalyte solution until end of surgery.
0.9% normal saline
In each group, patients received either 0.9% normal saline or plasmalyte solution until end of surgery.
plasmalyte
In each group, patients received either 0.9% normal saline or plasmalyte solution until end of surgery.
plasmalyte
In each group, patients received either 0.9% normal saline or plasmalyte solution until end of surgery.
Interventions
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0.9% normal saline
In each group, patients received either 0.9% normal saline or plasmalyte solution until end of surgery.
plasmalyte
In each group, patients received either 0.9% normal saline or plasmalyte solution until end of surgery.
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
2. pregnancy
3. breast feeding
4. lack of mental weakness(including disabled)
5. using diuretics
6. respiratory insufficiency
7. metabolic acidosis or alkalosis
8. coagulation disorder
9. over hydtration
10. renal failure or serum creatinine \> 1.4mg/dl
11. anemia (Hemoglobin 9.0\<mg/dl)
12. hypernatremia (Na \> 145mEq/L)
13. Hyperkalemia (K\>5.5mEq/L)
14. psychological medication or any drugs that influences renal clearance
20 Years
70 Years
ALL
Yes
Sponsors
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Yonsei University
OTHER
Responsible Party
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Locations
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Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine
Seoul, Seoul, South Korea
Countries
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References
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Song JW, Shim JK, Kim NY, Jang J, Kwak YL. The effect of 0.9% saline versus plasmalyte on coagulation in patients undergoing lumbar spinal surgery; a randomized controlled trial. Int J Surg. 2015 Aug;20:128-34. doi: 10.1016/j.ijsu.2015.06.065. Epub 2015 Jun 27.
Other Identifiers
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4-2012-0059
Identifier Type: -
Identifier Source: org_study_id
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