The Effect of Glaucoma Drops on of the Duration of a Pure Intraocular Gas Bubble

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

View full results

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

21 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-06-30

Study Completion Date

2013-04-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

A controlled clinical study comparing the effect of topical aqueous suppressants on intraocular gas duration.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Effect of Topical Aqueous Suppressants on Intraocular Gas Duration Following Pars Plana Vitrectomy

NCT01257698

Macular Hole Retinal Detachment

COMPLETED NA

Phase 2 Study of BL1107 Eye Drops vs. Timolol in Adults With Primary Open Angle Glaucoma or Ocular Hypertension

NCT07168902

Glaucoma

RECRUITING PHASE2

Comparison of the Effects of Two Glaucoma Drugs Over 24 Hours (0507A-137)(COMPLETED)

NCT00108017

Glaucoma Ocular Hypertension

COMPLETED PHASE3

Circadian Ocular Perfusion Pressure and Ocular Blood Flow

NCT00800540

Glaucoma

COMPLETED PHASE4

A Study of a Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension

NCT00314158

Open-angle Glaucoma Ocular Hypertension

COMPLETED PHASE3

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

A Prospective, Randomized Study Comparing the Effects of Topical Aqueous Suppressants on Intraocular Gas Duration following Scleral Buckling and Pneumatic Retinopexy

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Scleral Buckling

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Post surgery without glaucoma drops

This will be for the group that had gas duration surgery using SF6 (Sulfur Hexafluoride) or C3F8 (perfluoropropane gas tamponade) and only uses the standard post-operative topical drops.

Group Type ACTIVE_COMPARATOR

standard post-operative topical drops

Intervention Type DRUG

Patients will receive the standard post-operative drops regardless of what group ther are in. The standard post-operative drops are Prednisolone acetate,Polymyxin B and Trimethoprim

Post surgery with glaucoma drops

This will be for the group that had gas duration surgery (using SF6 or C3F8). In addition to the standard post-operative topical drops, glaucoma drops, Timolol-dorzolamide (timolol 0.5%-dorzolamide 2%) will be given.

Group Type EXPERIMENTAL

Timolol-dorzolamide (Glaucoma drops)

Intervention Type DRUG

Patients will receive the standard post-operative drops regardless of what group you are in. The glaucoma drops will only be given to the experimental group.

standard post-operative topical drops

Intervention Type DRUG

Patients will receive the standard post-operative drops regardless of what group ther are in. The standard post-operative drops are Prednisolone acetate,Polymyxin B and Trimethoprim

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Timolol-dorzolamide (Glaucoma drops)

Patients will receive the standard post-operative drops regardless of what group you are in. The glaucoma drops will only be given to the experimental group.

Intervention Type DRUG

standard post-operative topical drops

Patients will receive the standard post-operative drops regardless of what group ther are in. The standard post-operative drops are Prednisolone acetate,Polymyxin B and Trimethoprim

Intervention Type DRUG

Other Intervention Names

Discover alternative or legacy names that may be used to describe the listed interventions across different sources.

timol glaucoma drops dorzolamide timol-dorzolamide glaucoma drops standard of care oral corticosteroid prednisolone Polymyxin B trimethoprim

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Ability to provide written informed consent and comply with study assessments for the full duration of the study.
* Have undergone eye surgery including scleral buckling or pneumatic retinopexy for treatment of retinal detachment other condition at the discretion of the investigator.

Exclusion Criteria

* Prior surgery to treat glaucoma.
* Current use of glaucoma eye drops.
* Absence of a lens in the eye or presence of a lens implant in front of the iris (colored part of your eye).
* Allergy or contraindication to any of the glaucoma drops being used in this study (e.g., sulfa allergy, asthma, chronic obstructive pulmonary disease (bronchitis or emphysema), slow heart rate).

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No