Post- Approval Study on Patients Who Received a HeartWare HVAD® During IDE Trials

NCT ID: NCT01832610

Last Updated: 2019-07-11

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

101 participants

Study Classification

OBSERVATIONAL

Study Start Date

2013-01-31

Study Completion Date

2018-03-31

Brief Summary

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Patients will be approached to participate in this PAS after the HeartWare® Ventricular Assist System receives PMA approval for the indicated use as a bridge to cardiac transplantation.

Detailed Description

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Patients who participated in prior trials will be approached for this PAS as follows:

* Patients who are on continued HeartWare® System support, (original or exchange device)
* Patients who have been explanted for transplant or recovery and have not yet completed 6 months of follow-up

Patients who participated in prior trials who will not be approached to participate in this follow-up study include:

• Patients who have been explanted for transplant or recovery and have completed at least 6 months of follow-up (documented in the prior IDE trial).

No new patients are being screened or implanted with the HeartWare® System for this trial, it is a follow-up trial only.

Conditions

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Heart Failure

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

OTHER

Study Groups

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HeartWare® VAS

Ventricular Assist Device (HeartWare® VAS)

HeartWare® VAS

Intervention Type DEVICE

The HeartWare® LVAD is an implantable centrifugal pump that was designed to provide flows up to 10 L/min in a small device which is both lightweight and simple to use.

Interventions

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HeartWare® VAS

The HeartWare® LVAD is an implantable centrifugal pump that was designed to provide flows up to 10 L/min in a small device which is both lightweight and simple to use.

Intervention Type DEVICE

Other Intervention Names

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HVAD®

Eligibility Criteria

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Inclusion Criteria

1. The patient has participated in a prior HeartWare trial under IDE G070199.
2. The patient was implanted with the HeartWare® Ventricular Assist System and was an active patient in the prior trial.
3. The patient has signed informed consent for participation in the study.

Exclusion Criteria

1. The patient is unwilling or unable to comply with trial requirements.
2. The patient did not sign the informed consent.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Medtronic Cardiac Rhythm and Heart Failure

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Stanford University School of Medicine

Stanford, California, United States

Site Status

Washington Hospital Center

Washington D.C., District of Columbia, United States

Site Status

University of Florida - Gainesville

Gainesville, Florida, United States

Site Status

University of Miami / Jackson Memorial Hospital

Miami, Florida, United States

Site Status

The Emory Clinic Inc.

Atlanta, Georgia, United States

Site Status

Northwestern Memorial Hospital

Chicago, Illinois, United States

Site Status

University of Chicago

Chicago, Illinois, United States

Site Status

Advocate Christ Medical Center

Oak Lawn, Illinois, United States

Site Status

IU Health Methodist

Indianapolis, Indiana, United States

Site Status

Jewish Hospital - Rudd Heart and Lung Institute

Louisville, Kentucky, United States

Site Status

Tufts Medical Center

Boston, Massachusetts, United States

Site Status

University of Michigan Hospital

Ann Arbor, Michigan, United States

Site Status

Henry Ford Hospital

Detroit, Michigan, United States

Site Status

University of Minnesota

Minneapolis, Minnesota, United States

Site Status

Washington University / Barnes Jewish Hospital

St Louis, Missouri, United States

Site Status

Montefiore Medical Center

The Bronx, New York, United States

Site Status

Duke University Medical Center

Durham, North Carolina, United States

Site Status

Cleveland Clinic Foundation

Cleveland, Ohio, United States

Site Status

Ohio State University Medical Center

Columbus, Ohio, United States

Site Status

Milton S. Hershey Medical Center

Hershey, Pennsylvania, United States

Site Status

Hospital of the University of Pennsylvania

Philadelphia, Pennsylvania, United States

Site Status

University of Pittsburgh Medical Center

Pittsburgh, Pennsylvania, United States

Site Status

University of Texas - South Western

Dallas, Texas, United States

Site Status

Texas Heart Institute

Houston, Texas, United States

Site Status

Northwest Cardiothoracic &Transplant Surgeons

Spokane, Washington, United States

Site Status

Countries

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United States

Provided Documents

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Document Type: Study Protocol

View Document

Document Type: Statistical Analysis Plan

View Document

Other Identifiers

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HW-PAS-03

Identifier Type: -

Identifier Source: org_study_id

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