Differential Plasma MicroRNA Profiles in ED and Normal Erectile Function in Older Males

NCT ID: NCT01830049

Last Updated: 2013-04-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

30 participants

Study Classification

OBSERVATIONAL

Study Start Date

2013-03-31

Study Completion Date

2013-08-31

Brief Summary

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Erectile dysfunction (ED) is strongly associated with aging. With the rapidly expanding aging population and the increase in life expectancy, an increase in the prevalence of ED is expected in the years to come. Currently, the mechanism of ED is not fully understood. MicroRNAs (MiRNA) are endogenous small RNA molecules that control gene expression post-transcriptionally. It has been included in many in vitro physiology and pathophysiology processes, which also involved in the process of ED. This research was designed to investigate the differential plasma MiRNA profiles in ED and normal erectile function in older males. The results might tell us which MiRNA and how did it involved in the process of ED in aging.

Detailed Description

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Conditions

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Erectile Dysfunction

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Group I

Older males with ED

Take blood

Intervention Type OTHER

Group II

Older males with normal erectile function

Take blood

Intervention Type OTHER

Gourp III

Young males with normal rectile function

Take blood

Intervention Type OTHER

Interventions

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Take blood

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* older males with erectile dysfunction

Exclusion Criteria

* have some other general diseases, e.g. hypertension, vascular diseases, depression, chronic kidney disease, diabetes.
Minimum Eligible Age

20 Years

Maximum Eligible Age

80 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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Nanjing Medical University

OTHER

Sponsor Role lead

Responsible Party

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Feng Pan

MD.

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Nanjing Gulou Hospital affiliated to Nanjing University, Medical School

Nanjing, Jiangsu, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Feng Pan, Doctor

Role: CONTACT

0086-25-52226379

Facility Contacts

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Yutian Dai, Doctor

Role: primary

0086-25-52227777

Other Identifiers

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2013024

Identifier Type: OTHER

Identifier Source: secondary_id

NJU2013024

Identifier Type: -

Identifier Source: org_study_id

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