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Efficacy of JUC as Hand Rub Evaluated by Using European Standard 1500

NCT ID: NCT01824888

Last Updated: 2014-12-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE2

Total Enrollment

15 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-06-30

Study Completion Date

2012-12-31

Brief Summary

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JUC is a commercially available wound care spray. It is evaluated for the efficacy when using as a hygienic hand rub following the protocol described in the European standard EN 1500:1997 "Chemical disinfectants and antiseptics - Hygienic handrub - Test method and requirement (phase 2/step 2)". A crossover study to compare the JUC solution with 60% (v/v) propan-2-ol by using Escherichia coli K12 NCTC strain 10538 as test organism.

Detailed Description

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Before the intervention, the bactericidal activity of JUC was validated in accordance with the prEN 12054. A total of 15 volunteers were recruited, hands were washed immediately prior to the intervention. Then, both hands of each volunteer were immersed into a contamination fluid of E. coli. Then, hand rub was performed with JUC or alcohol. Culture samples were collected before and after the hand rub by rubbing the fingertips and thumb tips of each hand ont he base of a Petri dish containing appropriate medium. The culture inoculation, incubation, appropriate dilutions, and colony count were performed.

Conditions

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Infectious Disease Transmission

Keywords

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JUC hand rub European standard

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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Control

Following standard one-minute handwashing, both hands were immersed up to the mid-metacarpals for 5 seconds into a contamination fluid containing E. coli. Handrubs were performed by using 60% propan-2-ol into the cupped hands and rub vigorously for 30 seconds, the procedure was completed by a 5 seconds rinse of the fingers under running tap water and excess water was shaken off.

Group Type ACTIVE_COMPARATOR

propan-2-ol

Intervention Type DRUG

1.5 ml propan-2-ol rubbing on hands for 30 seconds, repeated twice

JUC solution

Following standard one-minute handwashing, both hands were immersed up to the mid-metacarpals for 5 seconds into a contamination fluid containing E. coli. Handrubs were performed by pouring 1.5 ml of JUC into the cupped hands and rub vigorously for 30 seconds, the procedure was completed by a 5 seconds rinse of the fingers under running tap water and excess water was shaken off.

Group Type EXPERIMENTAL

JUC solution

Intervention Type DRUG

1.5 ml JUC solution rubbing on hands for 30 seconds, repeated twice

Interventions

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JUC solution

1.5 ml JUC solution rubbing on hands for 30 seconds, repeated twice

Intervention Type DRUG

propan-2-ol

1.5 ml propan-2-ol rubbing on hands for 30 seconds, repeated twice

Intervention Type DRUG

Other Intervention Names

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JUC physical antimicrobial dressing alcohol reference

Eligibility Criteria

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Inclusion Criteria

* healthy and absence of significant illness

Exclusion Criteria

* Visible wounds on hands
Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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The Hong Kong Polytechnic University

OTHER

Sponsor Role lead

Responsible Party

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John Yuen

Assistant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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John Yuen, PhD

Role: PRINCIPAL_INVESTIGATOR

The Hong Kong Polytechnic University

Locations

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PolyU Biomedical Science Laboratory

Kowloon, , Hong Kong

Site Status

Countries

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Hong Kong

Other Identifiers

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8-ZDA4

Identifier Type: OTHER_GRANT

Identifier Source: secondary_id

JUC-001-EN1500

Identifier Type: -

Identifier Source: org_study_id