Vitamin D Levels in Frail Elderly Patients With a Hip Fracture

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

447 participants

Study Classification

OBSERVATIONAL

Study Start Date

2010-01-31

Study Completion Date

2012-09-30

Brief Summary

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The purpose of this study is to assess whether all frail elderly admitted with hip fracture has a vitamin D deficiency, and if s-25(OH)D deficiency increases the risk of hip fracture in frail elderly.

Frail elderly are defined as being 65 years of age or older, and living in nursing homes or senior housings.

The investigators' hypotheses state that:

1. Frail elderly with hip fractures will have a suboptimal level of vitamin D.
2. Frail elderly with hip fractures are more likely to have a suboptimal level of vitamin D than frail elderly without any hip fractures during the last ten years.

Detailed Description

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The study examined frail elderly patients, defined as 65 of age or older and living nursing homes or senior housings.

Cases where taken from a Randomised Controlled Trial (NCT01102010), where the included where frail elderly admitted with a hip fractures to the Orthopaedic Surgery Ward at Aarhus University Hospital.

Controls were frail elderly, without a hip fracture in the previous ten years, admitted to the Geriatric Ward at Aarhus University Hospital.

The investigators will look at all eligible patients' files and record their serum-25(OH)D levels upon admission.

According to sample size calculations 92 patients are needed in the case group, and 138 patients in the control group.

The inclusion period will be from the 18th of January 2010 to the 1st of October 2012 for both groups.

Conditions

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Hip Fracture Vitamin D Deficiency

Keywords

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Frail elderly Hip fracture Vitamin D Geriatrics

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

RETROSPECTIVE

Study Groups

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Hip fracture, Frail elderly, Non-supplemented

Frail elderly with a hip fracture who did not received vitamin D supplementation

No interventions assigned to this group

Hip fracture, Frail elderly, Supplemented

Frail elderly with a hip fracture who received vitamin D supplementation

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Aged 65 or older
* Living in nursing home or senior housing
* Admitted with hip fracture to the Orthopaedic Ward, Aarhus University Hospital

* Aged 65 or older
* Living in nursing home or senior housing
* Admitted to the Geriatric Ward, Aarhus University Hospital

Exclusion Criteria

* No serum-25(OH)D measurement upon admission

* No serum-25(OH)D measurement upon admission
* Hip fracture in the previous ten years

Minimum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Responsible Party

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Responsibility Role SPONSOR

Locations

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Reasearch Unit, Geriatric Department, Aarhus University Hospital

Aarhus, , Denmark

Site Status

Countries

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Denmark

Other Identifiers

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2007-58-0010

Identifier Type: OTHER

Identifier Source: secondary_id

HFVD2012

Identifier Type: -

Identifier Source: org_study_id