An Study of Aripiprazole in the Treatment of Methamphetamine Dependence

NCT ID: NCT01813656

Last Updated: 2015-02-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

PHASE4

Total Enrollment

10 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-09-30

Study Completion Date

2014-02-28

Brief Summary

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Methamphetamine substance use is common worldwide. No approved pharmacologic treatments for methamphetamine dependence exist. Aripiprazole are Second generation antipsychotics,but have different pharmacological effects of neurotransmitters.To determine whether mirtazapine would reduce methamphetamine use among mehtamphetamine addicts.

Detailed Description

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Methods:A Multiple-Center, Randomized, Double-Blind.

Conditions

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Methamphetamine Dependence

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Aripiprazole

Aripiprazole arm,5mg/pill,10mg/day.last12weeks.

Group Type EXPERIMENTAL

Aripiprazole

Intervention Type DRUG

Aripiprazole group,5mg/pill,10mg/day non-forced titration method,last 12weeks

Sugar pill

placebo arm,5mg/pill,10mg/day,last12weeks

Group Type PLACEBO_COMPARATOR

placebo

Intervention Type DRUG

placebo group,5mg/pill,10mg/day non-forced titration method,last 12 weeks

Interventions

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Aripiprazole

Aripiprazole group,5mg/pill,10mg/day non-forced titration method,last 12weeks

Intervention Type DRUG

placebo

placebo group,5mg/pill,10mg/day non-forced titration method,last 12 weeks

Intervention Type DRUG

Other Intervention Names

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Aopai H20041507

Eligibility Criteria

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Inclusion Criteria

1. Patients,Diagnostic and Statistical Manual of Mental Disorders 4thed. (DSM-IV) criteria for Methamphetamine dependence.
2. Must sign a Information consent form.
3. Required to provide detailed address and phone number

Exclusion Criteria

1. Serious organic disease.
2. Suicide ideation or hurt others.
3. Taking antipsychotic within two weeks before.
4. drug allergy to Risperidone or Aripiprazole.
5. pregnancy and breastfeeding women.
Minimum Eligible Age

19 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Wei Hao

OTHER

Sponsor Role lead

Responsible Party

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Wei Hao

The Second Xiangya Hospital of Cental South University

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Wei Hao, MD., Ph.D.

Role: STUDY_DIRECTOR

Central South University

Locations

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The Second Xiangya Hospital of Central University

Changsha, Hunan, China

Site Status

Countries

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China

Other Identifiers

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100000-068942

Identifier Type: -

Identifier Source: org_study_id

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