The Effects of L-arabinose in a Meal in Healthy Men

NCT ID: NCT01801540

Last Updated: 2013-02-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

17 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-12-31

Study Completion Date

2011-03-31

Brief Summary

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The purpose of this study is to investigate the effect of a meal containing different doses of L-arabinose, on the intestinal sucrase activity after intake We measure this by measuring the glucose, insulin and c-peptide after meals. Other measurements are made (glucagon and GLP-1) to explain the correlations.

Detailed Description

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Conditions

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Glucose Metabolism

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

PREVENTION

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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0% arabinose meal sucrose/starch

A meal containing a bon with butter and marmalade, a cup cake, The and water

Group Type EXPERIMENTAL

L-arabinose - effect on glucose metabolism

Intervention Type DIETARY_SUPPLEMENT

L-arabinose is mixed into the dough of the buns and cup cakes

5 % arabinose meal sucrose/starch

A meal containing a bon with butter and marmalade, a cup cake, The and water

Group Type OTHER

L-arabinose - effect on glucose metabolism

Intervention Type DIETARY_SUPPLEMENT

L-arabinose is mixed into the dough of the buns and cup cakes

10 % arabinose meal sucrose/starch

A meal containing a bon with butter and marmalade, a cup cake, The and water

Group Type OTHER

L-arabinose - effect on glucose metabolism

Intervention Type DIETARY_SUPPLEMENT

L-arabinose is mixed into the dough of the buns and cup cakes

0 % arabinose meal Starch

A meal containing two bons with butter and cheese, The and water

Group Type OTHER

L-arabinose - effect on glucose metabolism

Intervention Type DIETARY_SUPPLEMENT

L-arabinose is mixed into the dough of the buns and cup cakes

5 % arabinose meal starch

A meal containing two bons with butter and cheese, The and water

Group Type OTHER

L-arabinose - effect on glucose metabolism

Intervention Type DIETARY_SUPPLEMENT

L-arabinose is mixed into the dough of the buns and cup cakes

10 % arabinose meal starch

A meal containing two bons with butter and cheese, The and water

Group Type OTHER

L-arabinose - effect on glucose metabolism

Intervention Type DIETARY_SUPPLEMENT

L-arabinose is mixed into the dough of the buns and cup cakes

Interventions

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L-arabinose - effect on glucose metabolism

L-arabinose is mixed into the dough of the buns and cup cakes

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* Healthy male
* normal weight (BMI 18,5-25 kg/m2)
* 18-30 years of age

Exclusion Criteria

* Not healthy,including those with diabetes Mellitus, high bloodpressure, dyslipidemia or a infectious diseases (hepatitis or HIV), gastrointestinal disorders
* Central adipositas (defined as waist circumference \> 94 cm for european men)
* Daily intake of vitamins and minerals, 3 months before the trail starts and during the trail.
* elevated alcoholcunsumption(\> 21 units af alcohol pr. week)
* take medicine
* Elite athlete with intensive training
* given bloddonation within the last 3 months
* smoking
Minimum Eligible Age

18 Years

Maximum Eligible Age

30 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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University of Copenhagen

OTHER

Sponsor Role lead

Responsible Party

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AAstrup

Dr.Med.Sci./Ph.D.

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Jens Rikardt Andersen, MD, lector

Role: STUDY_DIRECTOR

Unit of Nutrition 5711, Rigshospitalet, Blegdamsvej 9, 2100 København Ø

Other Identifiers

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H-2-2010-095

Identifier Type: -

Identifier Source: org_study_id