Clinical Trial to Evaluate the Efficacy and Safety of DA-8031 in Male Patients With Premature Ejaculation

NCT ID: NCT01798667

Last Updated: 2013-08-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

PHASE2

Total Enrollment

220 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-01-31

Study Completion Date

2013-09-30

Brief Summary

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This study is designed to evaluate the efficacy and safety of DA-8031 and to decide the optimal dose of DA-8031 in male patients with premature ejaculation after oral administration on-demand.

The investigators hypothesized that newly-developed DA-8031 would effect in delaying ejaculation in patients with premature ejaculation (PE).

Design:

Placebo-controlled, Randomized, Double-blind, Double-dummy, Parallel group, Fixed dose design

Detailed Description

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Conditions

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Premature Ejaculation

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Placebo

PO administration

Group Type PLACEBO_COMPARATOR

Placebo

Intervention Type DRUG

Placebo of DA-8031, undistinguishable

DA-8031 dose 1

PO administration

Group Type EXPERIMENTAL

DA-8031

Intervention Type DRUG

DA-8031 dose 2

PO administration

Group Type EXPERIMENTAL

DA-8031

Intervention Type DRUG

DA-8031 dose 3

PO administration

Group Type EXPERIMENTAL

DA-8031

Intervention Type DRUG

Interventions

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DA-8031

Intervention Type DRUG

Placebo

Placebo of DA-8031, undistinguishable

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Male patients aged with premature ejaculation for more than 6 months.
* PEDT score ≥ 11

Exclusion Criteria

* IIEF-EF domain ≤ 21
* Serum Creatinine ≥ 2.5 mg/dl
* AST, ALT \> 3\*Upper limit of normal
* Subjects with hypotension(SBP/DBP\<90/50mmHg) or uncontrolled hypertension(SBP/DBP\>180/100mmHg)
* Subjects with chronic depression, psychiatric or schizophrenia,
* Subjects with alcohol, drug or substance abuse
Minimum Eligible Age

20 Years

Maximum Eligible Age

64 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

No

Sponsors

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Dong-A Pharmaceutical Co., Ltd.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Sae Woong Kim

Role: PRINCIPAL_INVESTIGATOR

Seoul St. Mary's Hospital

Du Geon Moon

Role: PRINCIPAL_INVESTIGATOR

Korea University Guro Hospital

Nam-Cheol Park

Role: PRINCIPAL_INVESTIGATOR

Pusan National University Hospital

Jae-Seung Paick

Role: PRINCIPAL_INVESTIGATOR

Seoul National University Hospital

Tai-Young Ahn

Role: PRINCIPAL_INVESTIGATOR

Asan Medical Center

Sung Won Lee

Role: PRINCIPAL_INVESTIGATOR

Samsung Medical Center

Ki Hak Moon

Role: PRINCIPAL_INVESTIGATOR

Yeongnam University Hospital

Kwangsung Park

Role: PRINCIPAL_INVESTIGATOR

Chonnam National University Hospital

Jong Kwan Park

Role: PRINCIPAL_INVESTIGATOR

Chonbuk National University Hospital

Dae Yul Yang

Role: PRINCIPAL_INVESTIGATOR

Kangdong Sacred Heart Hospital

Locations

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Samsung Medical Center

Seoul, , South Korea

Site Status RECRUITING

Countries

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South Korea

Central Contacts

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Sung Won Lee

Role: CONTACT

Email: [email protected]

Facility Contacts

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Sung Won Lee

Role: primary

Other Identifiers

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DA8031_PE_II

Identifier Type: -

Identifier Source: org_study_id