Genetics and Mechanisms of Rheumatoid Arthritis

NCT ID: NCT01788098

Last Updated: 2013-02-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

790 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-10-31

Study Completion Date

2012-12-31

Brief Summary

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The study is aimed at revealing genetic background in rheumatoid arthritis (RA). For that purpose samples of DNA will be collected from 500 RA patients and similar number of controls from whole Slovakia. Variations in several genes associated with RA will be evaluated. The second aim is to assess functional changes in immune cells from selected patients and their evaluation together with genetic background. The project has observational character without any intention to change the treatment of RA patients.

Detailed Description

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Conditions

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Rheumatoid Arthritis Leukocytes, Mononuclear Genetic Association Studies

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Rheumatoid Arthritis

Patients with rheumatoid arthritis

No interventions assigned to this group

Healthy controls

Healthy control subjects

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* rheumatoid arthritis or healthy
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Slovak Academy of Sciences

OTHER_GOV

Sponsor Role lead

Responsible Party

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Stefan Zorad

Head of Laboratory

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Richard Imrich

Role: STUDY_CHAIR

Slovak Academy of Sciences, Center for Molecular Medicine

Locations

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Slovak Academy of Sciences, Center for Molecular Medicine

Bratislava, , Slovakia

Site Status

Countries

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Slovakia

Other Identifiers

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ATMOS N00024

Identifier Type: OTHER_GRANT

Identifier Source: secondary_id

RASGENAS

Identifier Type: -

Identifier Source: org_study_id

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