Trama-Code (Two Analgesics-comparative Study)

NCT ID: NCT01782846

Last Updated: 2016-04-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

803 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-03-31

Study Completion Date

2013-04-30

Brief Summary

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Double-blind randomized study to compare the efficacy of two analgesic drugs(Ixprim®, Dafalgan-Codeine®) in the emergency unit.

The efficacy (relief of pain) would be assessed 2 hours after administration of one of the two drugs in a patient presented to the emergency unit with a moderate pain (4 to 6 on pain assessment score).

Detailed Description

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Conditions

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Pain

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Caregivers

Study Groups

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Ixprim®

2 capsules of Ixprim® given orally (1000 mg Paracetamol + 75 mg Tramadol)

Group Type ACTIVE_COMPARATOR

Ixprim®

Intervention Type DRUG

Dafalgan Codeine®

Two capsules of Dafalgan Codeine® given orally (1000 mg Paracetamol + 46.8 mg Codeine)

Group Type ACTIVE_COMPARATOR

Dafalgan-Codeine®

Intervention Type DRUG

Interventions

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Ixprim®

Intervention Type DRUG

Dafalgan-Codeine®

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Patients of 18 - 75 years of age
* Presented to the emergency unit of FOCH hospital
* Complaining of moderate pain (4-6 on pain assessment scale) evaluated by the reception nurse

Exclusion Criteria

* Patient already had received another type 2 analgesia or already received one of the study drugs in the last 4 hours
* pregnant or lactating females
* Patient with one or more contraindication to one of the study drugs
* Patients for whom the pain assessment scale can not be performed (unconscious, confused ...)
* Patient cannot be included for legal reasons
* Patient required urgent management
* Patient for whom it is considered difficult to be reassessed 2 hours later
* Patient unable to swallow
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Hopital Foch

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Hôpital FOCH - Emergency unit

Suresnes, Île-de-France Region, France

Site Status

Countries

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France

Other Identifiers

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2010/45

Identifier Type: -

Identifier Source: org_study_id

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