Trial Outcomes & Findings for Repair of Soft Tissue Defect of the Finger Using the Heterodigital Neurocutaneous Island Flap (NCT NCT01778296)

NCT ID: NCT01778296

Last Updated: 2024-02-14

Results Overview

Discriminatory sensation of the flap is evaluated with the Static 2-point Discrimination Test. The test determines the minimal distance at which a subject can sense the presence of two needles. The modified American Society for Surgery of the Hand guidelines were used to stratify Discriminator measurements (excellent \<6 mm; good 6-10 mm; fair 11-15 mm; poor \>15 mm. The test point is at the center of the flap. Each area was tested 3 times with a Discriminator (Ali Med, Dedham, MA). Two out of 3 correct answers were considered proof of perception before proceeding to another lower value. We stop at 4mm as a limit of 2PD and considered this normal. These assessments take place at a single time point at the final follow-up.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

12 participants

Primary outcome timeframe

18 months to 24 months

Results posted on

2024-02-14

Participant Flow

From February of 2008 to March of 2011,12 patients with soft tissue defects in the middle phalanx or the proximal interphalangeal joint were included in the study.The type of location is medical clinic. These patients were treated with the neurocutaneous island flap.

No wash out, run-in or transition happened in our study.

Participant milestones

Participant milestones
Measure
Surgical Flap
The neurocutaneous island flap is based on the dorsal branch of the digital nerve
Overall Study
STARTED
12
Overall Study
COMPLETED
12
Overall Study
NOT COMPLETED
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Repair of Soft Tissue Defect of the Finger Using the Heterodigital Neurocutaneous Island Flap

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Surgical Flap
n=12 Participants
The neurocutaneous island flap is based on the dorsal branch of the digital nerve
Age, Categorical
<=18 years
1 Participants
n=5 Participants
Age, Categorical
Between 18 and 65 years
11 Participants
n=5 Participants
Age, Categorical
>=65 years
0 Participants
n=5 Participants
Age, Continuous
34.5 years
STANDARD_DEVIATION 9.4 • n=5 Participants
Sex: Female, Male
Female
3 Participants
n=5 Participants
Sex: Female, Male
Male
9 Participants
n=5 Participants
Region of Enrollment
China
12 participants
n=5 Participants
Tissue reconstruction with the neurocutaneous island flap
12 participants
1.2 • n=5 Participants

PRIMARY outcome

Timeframe: 18 months to 24 months

Discriminatory sensation of the flap is evaluated with the Static 2-point Discrimination Test. The test determines the minimal distance at which a subject can sense the presence of two needles. The modified American Society for Surgery of the Hand guidelines were used to stratify Discriminator measurements (excellent \<6 mm; good 6-10 mm; fair 11-15 mm; poor \>15 mm. The test point is at the center of the flap. Each area was tested 3 times with a Discriminator (Ali Med, Dedham, MA). Two out of 3 correct answers were considered proof of perception before proceeding to another lower value. We stop at 4mm as a limit of 2PD and considered this normal. These assessments take place at a single time point at the final follow-up.

Outcome measures

Outcome measures
Measure
Surgical Flap
n=12 Participants
The neurocutaneous island flap is based on the dorsal branch of the digital nerve
Discriminatory Sensation of the Flap
8.3 mm
Standard Deviation 1.6

SECONDARY outcome

Timeframe: 18 months to 24 months

We access the cold intolerance of the injured and donor fingers using the self-administered Cold Intolerance Severity Score questionnaire10 that is rated into mild, moderate, severe, and extreme (0-25, 26-50, 51-75 and 76-100).

Outcome measures

Outcome data not reported

Adverse Events

Surgical Flap

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Dr. Chao Chen

The Second Hospital of Tangshan

Phone: 86-13700350471

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place