Phase 1 Study to Compare the Pharmacokinetic Characteristics and Food Effect of Pelubiprofen (30mg) Tablet IR TID and Pelubiprofen SR (as a Pelubiprofen 90 mg) Tablet QD in Healthy Subjects

NCT ID: NCT01776697

Last Updated: 2013-01-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE1

Study Classification

INTERVENTIONAL

Study Start Date

2012-03-31

Study Completion Date

2012-04-30

Brief Summary

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A randomized, open-labeled, comparative 3-way crossover study to compare the pharmacokinetic characteristics and food effect of pelubiprofen (30mg) tablet IR TID and pelubiprofen SR (as a pelubiprofen 90 mg) tablet QD in healthy subjects.

Detailed Description

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Conditions

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Healthy

Study Groups

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pelubiprofen (30mg) tablet IR TID, fasting

Group Type ACTIVE_COMPARATOR

pelubiprofen (30mg) tablet IR

Intervention Type DRUG

pelubiprofen (30mg) tablet IR TID, fed

Group Type ACTIVE_COMPARATOR

pelubiprofen (30mg) tablet IR

Intervention Type DRUG

pelubiprofen SR (as a pelubiprofen 90 mg) tablet QD

Group Type EXPERIMENTAL

pelubiprofen SR (as a pelubiprofen 90 mg) tablet

Intervention Type DRUG

Interventions

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pelubiprofen (30mg) tablet IR

Intervention Type DRUG

pelubiprofen SR (as a pelubiprofen 90 mg) tablet

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

1. Adult Healthy males aged 20\~45 years
2. weight over 45 kg, ideal body weight ±20%\[Ideal weight\] = \[Height(cm)-100\] X 0.9
3. Subjects who voluntarily agreed with written consent

Exclusion Criteria

1. Patients with acute disorder within 28 days before clinical trial drugs administration
2. History of disorders(inflammatory GI tract disease, stomach ulcer, gastrectomy, liver disease) which can affect ADME of drugs
3. Patients with active GI tract, cardiovascular, respiratory, renal, endocrinal, haematological, central nerval, psychiatric disease or malignant tumor
Minimum Eligible Age

20 Years

Maximum Eligible Age

45 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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Daewon Pharmaceutical Co., Ltd.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Other Identifiers

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DW330SR-1001(Ver2.2)

Identifier Type: -

Identifier Source: org_study_id

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