Evaluation of Non Specific Symptoms and Quality of Life Before and After Surgery for Mild Primary Hyperparathyroidism

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

116 participants

Study Classification

OBSERVATIONAL

Study Start Date

2007-12-31

Study Completion Date

2011-06-30

Brief Summary

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The purpose of this study is to evaluate the evolution of the non specific symptoms for 116 patients with mild primary hyperparathyroidism before and 3, 6 and 12 months after surgery. A clinical score predicting clinical improvement at one year will be created.

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Detailed Description

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Conditions

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Primary Hyperparathyroidism

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Patients with Hyperparathyroidism

The cohort of patients is made of patients with primary mild hyperparathyroidism and who have received a surgery at Nantes, Angers, Limoges or Marseille University Hospitals

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Subjects with known moderate HPTI will be considered for participation.

Patients with sporadic mild HPTI defined by:

* calcemia \> 2.6 mmol/L , PTH \> 25 ng/L and creatininemia \< 160µmol/L OR
* calcemia between 2.5 and 2.6 mmol/L and PTH \> 35 ng/L
* calcemia ≤2.85 mmol/L
* urine calcium level / 24 hours \< 10 mmol (400 mg),
* decrease of the creatinin's clearance : 30% lower than normal population with the same age
* patients younger than 50
* patients who can't be followed

Exclusion Criteria

* familial hypercalcemia
* multiple endocrinal neoplasia
* treatment with lithium or thiazides
* impossibility for the patient to complete the forms
* impossibility to follow the patient
* patient with serious disease which impact the quality of life

Maximum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No