Study of Two Surgical Drilling Techniques to Treat Juvenile Osteochondritis Dissecans of the Knee
NCT ID: NCT01754298
Last Updated: 2020-12-03
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
91 participants
INTERVENTIONAL
2013-01-18
2020-10-16
Brief Summary
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Detailed Description
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Conditions
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Keywords
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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Retro-articular drilling
Retro-articular drilling goes through the cortical margin of the affected condyle, thereby sparing the articular surface and physes.
Retro-articular drilling
* Drilling must be performed under AP and lateral fluoroscopic guidance, with no additional drilling in 'trans-articular', or intra-articular trans-condylar fashion.
* Use a 0.045 K-wire for drilling.
* Minimum of 8 wire passes per square centimeter with no maximum number of wire passes.
Trans-articular drilling
Trans-articular drilling penetrates the articular cartilage through multiple sites to create subchondral penetrations.
Trans-articular drilling
* Drilling must be performed, under arthroscopic visualization, directly through the articular cartilage, with no additional drilling in 'retro-articular', 'extra-articular', or trans-condylar (through the intercondylar notch)
* Use a 0.045 K-wire for drilling
* A minimum 4 wire passes per square centimeter, with a maximum of 5 wire passes per square centimeter
Interventions
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Retro-articular drilling
* Drilling must be performed under AP and lateral fluoroscopic guidance, with no additional drilling in 'trans-articular', or intra-articular trans-condylar fashion.
* Use a 0.045 K-wire for drilling.
* Minimum of 8 wire passes per square centimeter with no maximum number of wire passes.
Trans-articular drilling
* Drilling must be performed, under arthroscopic visualization, directly through the articular cartilage, with no additional drilling in 'retro-articular', 'extra-articular', or trans-condylar (through the intercondylar notch)
* Use a 0.045 K-wire for drilling
* A minimum 4 wire passes per square centimeter, with a maximum of 5 wire passes per square centimeter
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Lesion located on the lateral aspect of the medial femoral condyle,
* Lesion considered stable based on MRI,
* Patient deemed skeletally immature based on MRI,
* Completed a course of conservative therapy.
Exclusion Criteria
* Lesion healed sufficiently and surgery is not recommended,
* Prior surgery on the affected knee,
* Diagnosis of metabolic bone disorder (e.g. osteogenesis imperfecta),
* Diagnosis of sickle cell disease,
* History of prolonged corticosteroid or chemotherapy treatment,
8 Years
18 Years
ALL
No
Sponsors
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Pediatric Orthopaedic Society of North America
OTHER
University of Pennsylvania
OTHER
Tennessee Orthopedic Alliance
OTHER
Children's Hospital Medical Center, Cincinnati
OTHER
Children's Hospital and Health System Foundation, Wisconsin
OTHER
Washington University School of Medicine
OTHER
The Hospital for Sick Children
OTHER
Children's Hospital of Philadelphia
OTHER
Kaiser Permanente
OTHER
Rady Children's Hospital, San Diego
OTHER
St. Luke's Children's Hospital
OTHER
Medical College of Wisconsin
OTHER
Connecticut Children's Medical Center
OTHER
Hospital for Special Surgery, New York
OTHER
Boston Children's Hospital
OTHER
Responsible Party
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Benton Heyworth
Instructor in Orthopaedic Surgery
Principal Investigators
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Benton Heyworth, M.D.
Role: PRINCIPAL_INVESTIGATOR
Boston Children's Hospital
Locations
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Kaiser Permanente Los Angeles
Los Angeles, California, United States
Rady Children's Hospital
San Diego, California, United States
Rocky Mountain Hospital for Children
Centennial, Colorado, United States
Connecticut Children's Medical Center
Farmington, Connecticut, United States
St. Luke's Children's Hospital
Boise, Idaho, United States
Boston Children's Hospital
Boston, Massachusetts, United States
Washington University School of Medicine
St Louis, Missouri, United States
Hospital for Special Surgery
New York, New York, United States
Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, United States
Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, United States
University of Pennsylvania
Philadelphia, Pennsylvania, United States
Tennessee Orthopaedic Alliance
Nashville, Tennessee, United States
Medical College of Wisconsin
Milwaukee, Wisconsin, United States
The Hospital for Sick Children
Toronto, Ontario, Canada
Countries
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References
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Heyworth BE, Ganley TJ, Liotta ES, Hergott KA, Miller PE, Wall EJ, Myer GD, Nissen CW, Edmonds EW, Lyon RM, Chambers HG, Milewski MD, Green DW, Weiss JM, Wright RW, Polousky JD, Nepple JJ, Carey JL, Kocher MS; ROCK Group; Shea KG. Transarticular Versus Retroarticular Drilling of Stable Osteochondritis Dissecans of the Knee: A Prospective Multicenter Randomized Controlled Trial by the ROCK Group. Am J Sports Med. 2023 May;51(6):1392-1402. doi: 10.1177/03635465231165290. Epub 2023 Apr 11.
Related Links
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Research in OsteoChondritis of the Knee, OCD Study Group of North America
Other Identifiers
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IRB-P00004016
Identifier Type: -
Identifier Source: org_study_id