Trial Outcomes & Findings for Evaluation of the 755nm Alexandrite Laser for the Treatment of Tattoos (NCT NCT01754207)

NCT ID: NCT01754207

Last Updated: 2020-12-16

Results Overview

2D photography comparing pre and post treatment photos, where the percentage of tattoo clearance between the photos was determined by the evaluator.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

20 participants

Primary outcome timeframe

up to 3 months post last treatment

Results posted on

2020-12-16

Participant Flow

Participant milestones

Participant milestones
Measure
755nm Alexandrite Laser
755nm Alexandrite Laser 755nm Alexandrite Laser: 755nm Alexandrite Laser
Overall Study
STARTED
20
Overall Study
COMPLETED
17
Overall Study
NOT COMPLETED
3

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Evaluation of the 755nm Alexandrite Laser for the Treatment of Tattoos

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
755nm Alexandrite Laser
n=20 Participants
755nm Alexandrite Laser 755nm Alexandrite Laser: 755nm Alexandrite Laser 755nm Alexandrite Laser with CAP Array: 755nm Alexandrite Laser with CAP Array
Age, Categorical
<=18 years
0 Participants
n=5 Participants
Age, Categorical
Between 18 and 65 years
20 Participants
n=5 Participants
Age, Categorical
>=65 years
0 Participants
n=5 Participants
Sex: Female, Male
Female
15 Participants
n=5 Participants
Sex: Female, Male
Male
5 Participants
n=5 Participants
Race/Ethnicity, Customized
Race/Ethnicity · Caucasian
18 Participants
n=5 Participants
Race/Ethnicity, Customized
Race/Ethnicity · Hispanic
1 Participants
n=5 Participants
Race/Ethnicity, Customized
Race/Ethnicity · African American
1 Participants
n=5 Participants
Fitzpatrick Skin Type
Fitzpatrick Skin Score I
4 Participants
n=5 Participants
Fitzpatrick Skin Type
Fitzpatrick Skin Score II
9 Participants
n=5 Participants
Fitzpatrick Skin Type
Fitzpatrick Skin Score III
6 Participants
n=5 Participants
Fitzpatrick Skin Type
Fitzpatrick Skin Score IV
1 Participants
n=5 Participants
Fitzpatrick Skin Type
Fitzpatrick Skin Score V
0 Participants
n=5 Participants
Fitzpatrick Skin Type
Fitzpatrick Skin Score VI
0 Participants
n=5 Participants

PRIMARY outcome

Timeframe: up to 3 months post last treatment

2D photography comparing pre and post treatment photos, where the percentage of tattoo clearance between the photos was determined by the evaluator.

Outcome measures

Outcome measures
Measure
755nm Alexandrite Laser
n=23 Tattoos
755nm Alexandrite Laser 755nm Alexandrite Laser: 755nm Alexandrite Laser 755nm Alexandrite Laser with CAP Array: 755nm Alexandrite Laser with CAP Array
Tattoo Clearance Using Photographic Evaluation
>75% clearance
15 Tattoos
Tattoo Clearance Using Photographic Evaluation
51-74% clearance
6 Tattoos
Tattoo Clearance Using Photographic Evaluation
<25% clearance
2 Tattoos

Adverse Events

755nm Alexandrite Laser

Serious events: 0 serious events
Other events: 20 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Other adverse events
Measure
755nm Alexandrite Laser
n=20 participants at risk
755nm Alexandrite Laser 755nm Alexandrite Laser: 755nm Alexandrite Laser 755nm Alexandrite Laser with CAP Array: 755nm Alexandrite Laser with CAP Array
Nervous system disorders
Pain
45.0%
9/20 • Adverse Events occurring were captured for the study duration, around 12 months.
Adverse Events listed under "other" were monitored/assessed without regard to the specific Adverse Event Term.
Skin and subcutaneous tissue disorders
Erythema
80.0%
16/20 • Adverse Events occurring were captured for the study duration, around 12 months.
Adverse Events listed under "other" were monitored/assessed without regard to the specific Adverse Event Term.
Skin and subcutaneous tissue disorders
Pinpoint Bleeding
50.0%
10/20 • Adverse Events occurring were captured for the study duration, around 12 months.
Adverse Events listed under "other" were monitored/assessed without regard to the specific Adverse Event Term.
Skin and subcutaneous tissue disorders
Edema
80.0%
16/20 • Adverse Events occurring were captured for the study duration, around 12 months.
Adverse Events listed under "other" were monitored/assessed without regard to the specific Adverse Event Term.
Skin and subcutaneous tissue disorders
Crusting
75.0%
15/20 • Adverse Events occurring were captured for the study duration, around 12 months.
Adverse Events listed under "other" were monitored/assessed without regard to the specific Adverse Event Term.
Skin and subcutaneous tissue disorders
Scabbing
70.0%
14/20 • Adverse Events occurring were captured for the study duration, around 12 months.
Adverse Events listed under "other" were monitored/assessed without regard to the specific Adverse Event Term.
Skin and subcutaneous tissue disorders
Blistering
80.0%
16/20 • Adverse Events occurring were captured for the study duration, around 12 months.
Adverse Events listed under "other" were monitored/assessed without regard to the specific Adverse Event Term.
Skin and subcutaneous tissue disorders
Purpura
30.0%
6/20 • Adverse Events occurring were captured for the study duration, around 12 months.
Adverse Events listed under "other" were monitored/assessed without regard to the specific Adverse Event Term.
Skin and subcutaneous tissue disorders
Hypopigmentation
10.0%
2/20 • Adverse Events occurring were captured for the study duration, around 12 months.
Adverse Events listed under "other" were monitored/assessed without regard to the specific Adverse Event Term.
Skin and subcutaneous tissue disorders
Hyperpigmentation
15.0%
3/20 • Adverse Events occurring were captured for the study duration, around 12 months.
Adverse Events listed under "other" were monitored/assessed without regard to the specific Adverse Event Term.
Skin and subcutaneous tissue disorders
Bruising
5.0%
1/20 • Adverse Events occurring were captured for the study duration, around 12 months.
Adverse Events listed under "other" were monitored/assessed without regard to the specific Adverse Event Term.
Skin and subcutaneous tissue disorders
Other
10.0%
2/20 • Adverse Events occurring were captured for the study duration, around 12 months.
Adverse Events listed under "other" were monitored/assessed without regard to the specific Adverse Event Term.

Additional Information

Jamie Trimper

Cynosure

Phone: 800-886-2966

Results disclosure agreements

  • Principal investigator is a sponsor employee The PI cannot disclose confidential or proprietary information until after it becomes generally known or available to the public.
  • Publication restrictions are in place

Restriction type: OTHER