Trial Outcomes & Findings for Study Evaluating the Treatment of Occipital Neuralgia (NCT NCT01753765)

NCT ID: NCT01753765

Last Updated: 2024-01-24

Results Overview

Improvement of pain due to occipital neuralgia as measured on the Visual Analog Scale (VAS) for pain at Days 7 and 30 as compared to baseline (Day 0). 0= no pain, 10= worst pain imaginable. Higher scores equal worse outcome.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

26 participants

Primary outcome timeframe

Baseline to Day 7, Baseline to Day 30

Results posted on

2024-01-24

Participant Flow

Participant milestones

Participant milestones
Measure
Treatment
Study treatment with Cryo-Touch III device at Day 0. Device: Cryo-Touch III Study treatment at Day 0.: Device: Cryo-Touch III Study treatment at Day 0.
Overall Study
STARTED
26
Overall Study
COMPLETED
26
Overall Study
NOT COMPLETED
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Study Evaluating the Treatment of Occipital Neuralgia

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Treatment
n=26 Participants
Study treatment with Cryo-Touch III device at Day 0. Device: Cryo-Touch III Study treatment at Day 0.: Device: Cryo-Touch III Study treatment at Day 0.
Age, Continuous
49.1 years
STANDARD_DEVIATION 13.0 • n=5 Participants
Sex: Female, Male
Female
17 Participants
n=5 Participants
Sex: Female, Male
Male
9 Participants
n=5 Participants
Region of Enrollment
United States
26 participants
n=5 Participants
Average baseline Pain Visual Analog Scale (VAS)
6.3 units on a scale
STANDARD_DEVIATION 1.5 • n=5 Participants

PRIMARY outcome

Timeframe: Baseline to Day 7, Baseline to Day 30

Population: The variation in number analyzed at each timepoint from overall number of patients analyzed is due to the reflection of the actual number of participants with data collected at specified timepoint.

Improvement of pain due to occipital neuralgia as measured on the Visual Analog Scale (VAS) for pain at Days 7 and 30 as compared to baseline (Day 0). 0= no pain, 10= worst pain imaginable. Higher scores equal worse outcome.

Outcome measures

Outcome measures
Measure
Treatment
n=26 Participants
Study treatment with Cryo-Touch III device at Day 0. Device: Cryo-Touch III Study treatment at Day 0.: Device: Cryo-Touch III Study treatment at Day 0.
A Reduction in Either Pain Frequency or Severity Associated With Occipital Neuralgia.
Average Point Improvement Day 7
2.5 point improvement
Standard Deviation 2.5
A Reduction in Either Pain Frequency or Severity Associated With Occipital Neuralgia.
Average Point Improvement Day 30
2.7 point improvement
Standard Deviation 2.2

SECONDARY outcome

Timeframe: Day 30, Day 56

Treatment effect was based on Subject response when asked if the Subject had an effect from the treatment.

Outcome measures

Outcome measures
Measure
Treatment
n=26 Participants
Study treatment with Cryo-Touch III device at Day 0. Device: Cryo-Touch III Study treatment at Day 0.: Device: Cryo-Touch III Study treatment at Day 0.
Duration of Treatment
Day 30
13 Participants
Duration of Treatment
Day 56
9 Participants

Adverse Events

Treatment

Serious events: 0 serious events
Other events: 5 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Other adverse events
Measure
Treatment
n=26 participants at risk
Study treatment with Cryo-Touch III device at Day 0. Device: Cryo-Touch III Study treatment at Day 0.: Device: Cryo-Touch III Study treatment at Day 0.
Infections and infestations
Cold
3.8%
1/26 • Number of events 1 • Adverse events will be recorded from initiation of study treatment to Visit 5 Day 56- end of study
General disorders
Dizziness secondary to oral gabapentin medicine
3.8%
1/26 • Number of events 1 • Adverse events will be recorded from initiation of study treatment to Visit 5 Day 56- end of study
Injury, poisoning and procedural complications
Increased knee pain secondary to fall
3.8%
1/26 • Number of events 1 • Adverse events will be recorded from initiation of study treatment to Visit 5 Day 56- end of study
Infections and infestations
upper respiratory tract infection
3.8%
1/26 • Number of events 1 • Adverse events will be recorded from initiation of study treatment to Visit 5 Day 56- end of study
Injury, poisoning and procedural complications
pain in treatment area
3.8%
1/26 • Number of events 1 • Adverse events will be recorded from initiation of study treatment to Visit 5 Day 56- end of study
Injury, poisoning and procedural complications
increased pain in neck area
3.8%
1/26 • Number of events 1 • Adverse events will be recorded from initiation of study treatment to Visit 5 Day 56- end of study

Additional Information

Medical Information

Pacira Bioscience, Inc.

Phone: 1-855-793-9729

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place

Restriction type: LTE60