Can Fish Oil and Phytochemical Supplements Mimic Anti-Aging Effects of Calorie Restriction?

NCT ID: NCT01752868

Last Updated: 2012-12-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

56 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-05-31

Study Completion Date

2012-08-31

Brief Summary

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The purpose of this study is to determine if a combination of 10 nutritional supplements provide health benefits that are consistent with protection against age-related disease. All supplements have been shown in previous studies to have health benefits when administered alone. The hypothesis is that 6 months of taking 10 nutritional supplements each day will provide beneficial changes in healthy related measures.

Detailed Description

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Conditions

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Healthy Volunteers

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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supplement

Group Type EXPERIMENTAL

Supplement

Intervention Type DIETARY_SUPPLEMENT

Participants in this group will take the following nutritional supplements on a daily basis: curcumin, fish oil, resveratrol, sesamin, Acetyl-L-carnitine, lipoic acid, green and black teas, quercetin, pomegranate, cinnamon bark.

control

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Supplement

Participants in this group will take the following nutritional supplements on a daily basis: curcumin, fish oil, resveratrol, sesamin, Acetyl-L-carnitine, lipoic acid, green and black teas, quercetin, pomegranate, cinnamon bark.

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* age 40-60 yr
* body mass index of 21 - 30 kg/m2
* sedentary to moderately active
* eating a typical US diet

Exclusion Criteria

* history of any chronic disease other than mild osteoarthritis
* use of medications other than occasional use of non-steroidal anti-inflammatory drugs, antihistamines, antacids or laxatives
* use of nutritional supplements
* smoking
* alcohol intake greater than two drinks per day for women and three drinks per day for men
Minimum Eligible Age

40 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Barnes-Jewish Hospital

OTHER

Sponsor Role collaborator

Washington University School of Medicine

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Luigi Fontana, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Washington University School of Medicine

Locations

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Washington University Medical Center

St Louis, Missouri, United States

Site Status

Countries

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United States

Other Identifiers

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BJH 6936-33

Identifier Type: -

Identifier Source: org_study_id