Effectiveness of Garlic Oil in the Treatment of Arsenical Palmer Keratosis
NCT ID: NCT01748669
Last Updated: 2012-12-12
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE2
60 participants
INTERVENTIONAL
2011-10-31
2012-07-31
Brief Summary
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Detailed Description
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Twenty patients of mild to moderate degree of arsenical palmer keratosis will be treated with garlic oil in soft capsule (10 mg/day) orally for 12 weeks. Similar treatment will be given to 20 arsenic exposed controls and 20 healthy volunteers for comparison. The aim of this study is to examine the effectiveness of oral administration of garlic oil to reduce body arsenic load and clinical symptoms of arsenical palmer keratosis.
Conditions
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Keywords
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Study Design
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NON_RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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Patients of palmer arsenical keratosis
One soft capsule of garlic oil (10 mg) daily for 12 weeks
Garlic oil
Oral administration
Arsenic exposed controls
One soft capsule of garlic oil (10 mg) daily for 12 weeks
Garlic oil
Oral administration
Heathy volunteers
One soft capsule of garlic oil (10 mg) daily for 12 weeks
Garlic oil
Oral administration
Interventions
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Garlic oil
Oral administration
Eligibility Criteria
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Inclusion Criteria
* patients having mild to moderate arsenical keratosis present on palm of the hand
* patients those voluntarily agree to participate
* family member of the patient
* drinking arsenic contaminated water from the same source as patient
* those voluntarily agree to participate
* no sign/symptom of palmer keratosis
* drinking arsenic safe water (\<50 ppb)
* those voluntarily agree to participate
Exclusion Criteria
* lactating mother
* patient receiving treatment of arsenicosis
* any other chronic disease like tuberculosis, diabetes mellitus, bronchial asthma
20 Years
60 Years
ALL
Yes
Sponsors
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Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
OTHER
Responsible Party
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Prof. Mir Misbahuddin
Prof. and Chairman, Department of Pharmacology
Principal Investigators
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Mir Misbahuddin, MBBS, PhD
Role: PRINCIPAL_INVESTIGATOR
Department of Pharmacology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh.
Locations
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Bangabandhu Sheikh Mujib Medical University
Dhaka, , Bangladesh
Countries
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Other Identifiers
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BSMMU-005-CT
Identifier Type: -
Identifier Source: org_study_id