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Delayed-Enhancement Cardiovascular Magnetic Resonance in Patients With Sarcoidosis

NCT ID: NCT01745237

Last Updated: 2025-04-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

27000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2002-09-30

Study Completion Date

2032-06-30

Brief Summary

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The primary objective of this study was to determine the ability of cardiac magnetic resonance (CMR) to identify cardiac involvement in patients with sarcoidosis. Patients were to undergo CMR in addition to routine clinical evaluation.

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Detailed Description

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In patients with sarcoidosis, cardiac death is a leading cause of mortality which may represent unrecognized cardiac involvement. Cardiovascular magnetic resonance (CMR) can detect cardiac involvement including minute amounts of myocardial damage. Therefore, the objective of this study was to determine the usefulness of CMR and compare it with standard clinical evaluation for cardiac involvement. Patients with documented extracardiac sarcoidosis or clinically suspected cardiac sarcoidosis will be enrolled.

Conditions

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Sarcoidosis

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Biopsy proven sarcoidosis
* Suspected cardiac sarcoidosis

Exclusion Criteria

* Contraindication to MRI
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Duke University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Raymond J Kim, MD

Role: PRINCIPAL_INVESTIGATOR

Duke Cardiovascular Magnetic Resonance Center, Duke University Medical Center

Locations

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Duke University Medical Center

Durham, North Carolina, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Han W Kim, MD

Role: CONTACT

[email protected]
919-668-3539

Raymond J. Kim, MD

Role: CONTACT

[email protected]
919-668-3539

Facility Contacts

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Han W Kim, MD

Role: primary

[email protected]
919-668-3539

Raymond J Kim, MD

Role: backup

[email protected]
919-668-3539

References

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Patel MR, Cawley PJ, Heitner JF, Klem I, Parker MA, Jaroudi WA, Meine TJ, White JB, Elliott MD, Kim HW, Judd RM, Kim RJ. Detection of myocardial damage in patients with sarcoidosis. Circulation. 2009 Nov 17;120(20):1969-77. doi: 10.1161/CIRCULATIONAHA.109.851352. Epub 2009 Nov 2.

Reference Type RESULT
PMID: 19884472 (View on PubMed)

Other Identifiers

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DCMRC-8224a

Identifier Type: OTHER

Identifier Source: secondary_id

Pro00008224

Identifier Type: -

Identifier Source: org_study_id

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