Subconjunctival Bevacizumab and Recurrent Pterygium

NCT ID: NCT01744756

Last Updated: 2012-12-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE2/PHASE3

Total Enrollment

36 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-02-29

Study Completion Date

2012-09-30

Brief Summary

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A study to research whether subconjunctival bevacizumab injection may potentially suppress neovascularization in pterygium, retarding and decreasing the size of recurrent pterygium.

Detailed Description

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1. Pacients with recurrent pterygium
2. Anti-VEGF therapy -Bevacizumab

Conditions

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Recurrent Pterygium

Keywords

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Subconjunctival Bevacizumab Recurrent pterygium

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Subconjunctival Bevacizumab

One aplication of subconjunctival Bevacizumab 0,5 ml

Group Type EXPERIMENTAL

Bevacizumab

Intervention Type DRUG

One subconjunctival aplication of Bevacizumabe 0,5ml

Interventions

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Bevacizumab

One subconjunctival aplication of Bevacizumabe 0,5ml

Intervention Type DRUG

Other Intervention Names

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Avastin

Eligibility Criteria

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Inclusion Criteria

* Recurrent pterygium

Exclusion Criteria

* Pregnant or lactating women
* History of myocardial infarction
* History of stroke
Minimum Eligible Age

40 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Instituto de Olhos de Goiania

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Larissa S Stival, MD

Role: STUDY_CHAIR

Instituto de Olhos de Goiania

Locations

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Instituto de Olhos de Goiania

Goiânia, Goiás, Brazil

Site Status

Countries

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Brazil

References

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Stival LR, Lago AM, Figueiredo MN, Bittar RH, Machado ML, Nassaralla Junior JJ. Efficacy and safety of subconjunctival bevacizumab for recurrent pterygium. Arq Bras Oftalmol. 2014 Jan-Feb;77(1):4-7. doi: 10.5935/0004-2749.20140003.

Reference Type DERIVED
PMID: 25076364 (View on PubMed)

Other Identifiers

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pterygium bevacizumab

Identifier Type: -

Identifier Source: org_study_id