Clinical Study for the Impact of Bio-absorbable Felt (NEOVEIL®) With Fibrin Sealant on Removal of Drainage Tube After Minimally Invasive Gastrectomy for Gastric Cancer

NCT ID: NCT01742806

Last Updated: 2012-12-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

120 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-10-31

Study Completion Date

2013-06-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

This study is to evaluate if Bio-absorbable Felt(NEOVEIL®) makes the amount of exudate reduce and shortens time until drain removal after minimally invasive surgery for early gastric cancer.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

We investigate the effect on drainage amount of Bio-absorbable Felt(NEOVEIL®) after D1+b or D2 lymphadenectomy with distal gastrectomy for early gastric cancer.

This study is an randomised controlled trial undertaken in 7 centers in South Korea. Patients with stage I-II gastric cancer who is going to have curative distal gastrectomy with D1+b or D2 lymphadenectomy are randomly assigned to use bio-absorbable felt(NEOVEIL®) or not to use it. Block randomisation will be done by a central interactive computerised system, stratified by center.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Gastric Cancer

Keywords

Explore important study keywords that can help with search, categorization, and topic discovery.

Gastric cancer Minimally invasive surgery Distal gastrectomy Bio-absorbable Felt

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

control

not to use bio-absorbable felt(NEOVEIL®)

Group Type NO_INTERVENTION

No interventions assigned to this group

NEOVEIL®

To use bio-absorbable felt

Group Type EXPERIMENTAL

bio-absorbable felt(NEOVEIL®)

Intervention Type DEVICE

To cover bio-absorbable felt over the lymphadenectomy area (hepatoduodenal ligament, #5 and 12/gastroduodenal artery, #6/ pancreas head /suprapancreatic area, #7,8 and 9)

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

bio-absorbable felt(NEOVEIL®)

To cover bio-absorbable felt over the lymphadenectomy area (hepatoduodenal ligament, #5 and 12/gastroduodenal artery, #6/ pancreas head /suprapancreatic area, #7,8 and 9)

Intervention Type DEVICE

Other Intervention Names

Discover alternative or legacy names that may be used to describe the listed interventions across different sources.

bio-absorbable polyglicolic acid felt,NEOVEIL®

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* histologic confirmed gastric adenocarcinoma
* Patients who underwent laparoscopic distal gastrectomy.
* preoperative clinical stage I diagnosed with esophagogastroduodenoscopy,endoscopic ultrasonography and computerized tomography.
* patients who underwent more than D1+b lymphadenectomy

Exclusion Criteria

* Vulnerable participants (pregnant women, under 20 year old, and so on)
* liver or renal disease (Ex. liver cirrhosis, end stage renal disease)
* Transfusion is needed preoperatively or postoperatively due to bleeding
* Preoperative or intraoperative evaluation confirm ascites.
* Patients who use anticoagulant preoperatively or postoperatively
Minimum Eligible Age

20 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Yonsei University

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

WOO JIN HYUNG, M.D. Ph.D.

Role: PRINCIPAL_INVESTIGATOR

Yonsei University

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Seoul National University College of Medicine, Bundang Hospital

Seongnam-si, Gyenggi-do, South Korea

Site Status RECRUITING

Ajou University Medical Center

Suwon, Gyeonggi-do, South Korea

Site Status RECRUITING

Soonchunhyang University College of Medicine, Bucheon Hospital

Bucheon-si, , South Korea

Site Status RECRUITING

Dong-A University College of Medicine

Busan, , South Korea

Site Status RECRUITING

Seoul National University College of Medicine, Seoul National University Hospital

Seoul, , South Korea

Site Status NOT_YET_RECRUITING

The Catholic University of Korea, Yeouido St. Mary's Hospital

Seoul, , South Korea

Site Status RECRUITING

Yonsei University Health System, Severance Hospital

Seoul, , South Korea

Site Status RECRUITING

Countries

Review the countries where the study has at least one active or historical site.

South Korea

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

WOO JIN HYUNG, M.D. Ph.D.

Role: CONTACT

Phone: 82-2-2228-2129

Email: [email protected]

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Hyung-Ho Kim, M.D., Ph.D.

Role: primary

Sang-Uk Han, M.D., Ph.D.

Role: primary

Gyu Seok Cho, M.D., Ph.D.

Role: primary

Min-Chan Kim, M.D., Ph.D.

Role: primary

Hyuk-Joon Lee, M.D., Ph.D.

Role: primary

WOOK KIM, M.D. Ph.D.

Role: primary

WOO JIN HYUNG, M.D., Ph.D.

Role: primary

References

Explore related publications, articles, or registry entries linked to this study.

Nakamura T, Shimizu Y, Watanabe S, Hitomi S, Kitano M, Tamada J, Matsunobe S. New bioabsorbable pledgets and non-woven fabrics made from polyglycolide (PGA) for pulmonary surgery: clinical experience. Thorac Cardiovasc Surg. 1990 Apr;38(2):81-5. doi: 10.1055/s-2007-1013999.

Reference Type BACKGROUND
PMID: 2161571 (View on PubMed)

Hayashibe A, Sakamoto K, Shinbo M, Makimoto S, Nakamoto T. New method for prevention of bile leakage after hepatic resection. J Surg Oncol. 2006 Jul 1;94(1):57-60. doi: 10.1002/jso.20548.

Reference Type BACKGROUND
PMID: 16788945 (View on PubMed)

Ueda K, Tanaka T, Li TS, Tanaka N, Hamano K. Sutureless pneumostasis using bioabsorbable mesh and glue during major lung resection for cancer: who are the best candidates? J Thorac Cardiovasc Surg. 2010 Mar;139(3):600-5. doi: 10.1016/j.jtcvs.2009.06.021. Epub 2009 Aug 4.

Reference Type BACKGROUND
PMID: 19656529 (View on PubMed)

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

1-2012-0017

Identifier Type: -

Identifier Source: org_study_id