Effect of Lozenges Containing Probiotic Lactobacilli on Enamel Demineralization Assed by QLF
NCT ID: NCT01738958
Last Updated: 2014-12-03
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
66 participants
INTERVENTIONAL
2012-09-30
2014-03-31
Brief Summary
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It can be difficult to measure the increased porosity of the enamel by tooth decay, but this can be done using quantitative laser fluorescence (QLF). The method is based on visible light with a wavelength of 370 nm, addressing enamel. This produces an image consisting of red and green color tones and the dominant color of the enamel is green. Increased porosity of the enamel, resulting in a reduction of the auto-fluorescence and the loss (or gain) of the mineral can be quantified by means of a corresponding software.
The purpose of this study is to investigate the effect of a daily supplement of probiotic lactic acid bacteria on the loss of mineral in enamel assessed with QLF. The null hypothesis is that the mineral content will not differ from baseline in either the test group or the placebo group.
Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
QUADRUPLE
Study Groups
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Probiotic lactobacilli
L. reuteri, two times a day for 6 weeks
L. retueri
two tablets a day for 6 weeks
Placebo
Placebo tablets, two times a day for 6 weeks
Placebo
Interventions
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L. retueri
two tablets a day for 6 weeks
Placebo
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
12 Years
17 Years
ALL
Yes
Sponsors
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University of Copenhagen
OTHER
Responsible Party
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Mette Kirstine Keller
Assistant Professor
Locations
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Ishøj kommunale tandpleje
Ishøj, , Denmark
Countries
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Other Identifiers
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H-4-2012-096
Identifier Type: -
Identifier Source: org_study_id