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Influence of Medication Taste on Pediatric Prescribers' Prescribing Habits

NCT ID: NCT01734759

Last Updated: 2013-10-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE1

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-11-30

Study Completion Date

2013-01-31

Brief Summary

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The purpose of this study is to see if a medication taste test influences the prescribing habits of pediatric prescribers at Mayo Clinic.

Detailed Description

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Conditions

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Healthy

Keywords

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medication palatability medication taste

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

HEALTH_SERVICES_RESEARCH

Blinding Strategy

NONE

Study Groups

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Taste Test

Group Type EXPERIMENTAL

Taste Test

Intervention Type DRUG

Before the taste test each participant will fill out an informed consent form and an enrollment survey. Each participant will receive 0.5 mL of each study medication in the taste test. During the taste test each medication in a class will be labeled with a color name so as to prevent any bias from preconceived taste perception. They will record their perception of the medications taste on a visual analog scale (VAS). An anaphlyaxis kit will be on hand in case of emergencies. Between samples participants will cleanse their palate with a saltine cracker and 30 mL of water. 5 different classes of medications will be tested.

Medications to be sampled and the corresponding dose of the test dose are:

* Cephalosporins: cefdinir 12.5 mg, cefixime 10 mg
* Penicillins: penicillin VK 12.5 mg, amoxicillin 12.5 mg
* Analgesic/antipyretics: acetaminophen 16 mg, ibuprofen 10 mg
* Steroids: prednisolone 1.5 mg, prednisone 0.5 mg
* H2 receptor blockers: famotidine 4 mg, ranitidine 7.5 mg

Interventions

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Taste Test

Before the taste test each participant will fill out an informed consent form and an enrollment survey. Each participant will receive 0.5 mL of each study medication in the taste test. During the taste test each medication in a class will be labeled with a color name so as to prevent any bias from preconceived taste perception. They will record their perception of the medications taste on a visual analog scale (VAS). An anaphlyaxis kit will be on hand in case of emergencies. Between samples participants will cleanse their palate with a saltine cracker and 30 mL of water. 5 different classes of medications will be tested.

Medications to be sampled and the corresponding dose of the test dose are:

* Cephalosporins: cefdinir 12.5 mg, cefixime 10 mg
* Penicillins: penicillin VK 12.5 mg, amoxicillin 12.5 mg
* Analgesic/antipyretics: acetaminophen 16 mg, ibuprofen 10 mg
* Steroids: prednisolone 1.5 mg, prednisone 0.5 mg
* H2 receptor blockers: famotidine 4 mg, ranitidine 7.5 mg

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* subjects possess prescriptive authority (e.g. MD, nurse practitioner, physician's assistant, medication therapy management pharmacists)
* subjects have prescribed at least one of the study medications from one of the medication classes to pediatric patients at an outpatient clinic in the three months preceding the study

Exclusion Criteria

* subjects do not prescribe any of the tested medications
* subject has an allergy to all of the study medications
* subject is pregnant or breastfeeding
* subject has a medical condition that prevents them from being involved in the taste test

Participants are advised to be within or accessible to the Rochester, MN area during study recruitment and accessible afterwards via mail, email or fax.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Mayo Clinic

OTHER

Sponsor Role lead

Responsible Party

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Bernard Lee

Principle Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Bernard Lee, PharmD, RPh

Role: PRINCIPAL_INVESTIGATOR

Mayo Clinic

Ole J Olson, Pharm.D., BCPS

Role: PRINCIPAL_INVESTIGATOR

Mayo Clinic

Michelle J LoTurco, Pharm.D.

Role: STUDY_DIRECTOR

Mayo Clinic

Locations

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Mayo Clinic in Rochester

Rochester, Minnesota, United States

Site Status

Countries

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United States

Other Identifiers

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12-005823

Identifier Type: -

Identifier Source: org_study_id