Pathogenesis of Hematologic Malignancies

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ENROLLING_BY_INVITATION

Total Enrollment

5000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2008-09-30

Brief Summary

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The cause of blood and bone marrow cancers is poorly understood; however, most research focuses on how cancer cells grow and develop. Because the causes of these cancers are unknown, current treatments may be unnecessarily harsh and often do not provide a cure. Identifying the causes of blood cancers would allow for the development of treatments that are more likely to provide a cure. To find the causes of blood and bone marrow cancers, we will look for specific cancer cell abnormalities that are responsible for cancer cell growth. We will then look to see if drugs that can reverse these abnormalities can kill cancer cells.

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Detailed Description

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Conditions

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Acute Leukemia Lymphoproliferative Disorders Myeloproliferative Disorders Myelodysplastic Syndromes

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Blood Draw

blood draw, bone marrow procedure, or tissue biopsy

Intervention Type PROCEDURE

Interventions

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blood draw, bone marrow procedure, or tissue biopsy

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Suspected or confirmed diagnosis of AL, LPD, MDS, or MPD
* Male or female of all ages
* Willing and able to sign informed consent
* Willing guardian consent for participants under 18 years of age

Exclusion Criteria

* No suspected or confirmed diagnosis of acute leukemias (AL), lymphoproliferative disorders (LPD), myelodysplastic syndromes (MDS), or myeloproliferative diseases (MPD)

Minimum Eligible Age

1 Year

Eligible Sex

ALL

Accepts Healthy Volunteers

No