Safety and Efficacy of IQP-LH-101 in Postprandial Heartburn

NCT ID: NCT01718639

Last Updated: 2013-03-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

41 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-10-31

Study Completion Date

2013-03-31

Brief Summary

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This study is a randomized, placebo-controlled, single-blind, three-way crossover clinical trial to evaluate safety and efficacy of IQP-LH-101 (tablet form and liquid form) in postprandial heartburn.

The null hypothesis is that there is no difference between IQP-LH-101 and the placebo in terms of efficacy for postprandial heartburn treatment.

Detailed Description

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Conditions

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Postprandial Heartburn

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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IQP-LH-101 tablet

4 chewable tablets to be chewed thoroughly before swallowing

Group Type ACTIVE_COMPARATOR

IQP-LH-101 tablet

Intervention Type DEVICE

Oral medical device in the form of a chewable tablet

IQP-LH-101 liquid

2 liquid sachets to be emptied into the mouth and consumed.

Group Type ACTIVE_COMPARATOR

IQP-LH-101 liquid

Intervention Type DEVICE

Oral medical device in the form of a liquid

Placebo

1 tablet to be swallowed with water.

Group Type PLACEBO_COMPARATOR

Placebo

Intervention Type OTHER

Interventions

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IQP-LH-101 tablet

Oral medical device in the form of a chewable tablet

Intervention Type DEVICE

IQP-LH-101 liquid

Oral medical device in the form of a liquid

Intervention Type DEVICE

Placebo

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Post-prandial heartburn (e.g. after a high-fat meal) in at least 2 months prior to the study (at least 2 times a week)
* Not receiving prescribed treatment for heartburn, reflux or upper gastrointestinal disorders
* Written informed consent is a prerequisite for subject enrollment.

Exclusion Criteria

* Gastrointestinal bleeding within 12 months prior to the study
* Difficulty swallowing (dysphagia)
* History of or symptoms suggestive of Zollinger-Ellison syndrome, oesophageal or gastric malignancy, gastric or duodenal ulcer, pernicious anaemia, Barrett's oesophagus or systemic sclerosis
* Participation in other studies within the last 30 days prior to entry or during the study
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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InQpharm Group

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Weißenseerweg 111

Berlin, State of Berlin, Germany

Site Status

Countries

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Germany

Other Identifiers

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INQ/012512

Identifier Type: -

Identifier Source: org_study_id

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