Genetic Polymorphism as Moderator of the Effect of an Acute Bout of Exercise on Cognitive Function

NCT ID: NCT01718405

Last Updated: 2012-10-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

150 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-11-30

Study Completion Date

2017-11-30

Brief Summary

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Studies have shown that an acute bout of aerobic exercise positively effects cognition, mainly executive functioning; however the effect is not observed among all people and it is not clear whether only aerobic exercise can produce this effect or possibly also resistant exercise. The main purpose of our study is to examine whether genetic variation is a moderator of this effect and whether resistant exercise is comparable to aerobic exercise in improving cognition following a single bout of exercise.

Detailed Description

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Conditions

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Executive Function

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

BASIC_SCIENCE

Study Groups

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Exercise Group

Each individual subject will give a blood sample for genetic analysis and undertake an exercise session and a rest session as a control. Cognitive function will be tested before and after each session.

Group Type EXPERIMENTAL

Cognitive function after exercise test

Intervention Type OTHER

The individual subjects will participate in 3 sessions of either aerobic exercise, resistance exercise or rest, in a random order. Before and after each session, the subject will take computerized cognitive tests.

Blood sample analysis

Intervention Type GENETIC

In the first evaluation session blood samples will be taken from each subject and will be analysed for genetic polymorphism.

Interventions

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Cognitive function after exercise test

The individual subjects will participate in 3 sessions of either aerobic exercise, resistance exercise or rest, in a random order. Before and after each session, the subject will take computerized cognitive tests.

Intervention Type OTHER

Blood sample analysis

In the first evaluation session blood samples will be taken from each subject and will be analysed for genetic polymorphism.

Intervention Type GENETIC

Eligibility Criteria

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Inclusion Criteria

* Physical Education Students
* Able to sign consent form

Exclusion Criteria

* Competitive athletes
* Smokers
* Neurologic or psychologic orders
* Chronic diseases
* Head Injuries
* Hospitalization in the previous 3 months
* Pregnant
Minimum Eligible Age

20 Years

Maximum Eligible Age

35 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Hillel Yaffe Medical Center

OTHER_GOV

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Wingate Institute

Netanya, , Israel

Site Status

Countries

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Israel

Central Contacts

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Sharon Tsuk, PhD

Role: CONTACT

Phone: 972-522-640642

Email: [email protected]

Other Identifiers

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0049

Identifier Type: -

Identifier Source: org_study_id