Trial Outcomes & Findings for Corneal Incisions With the IntraLase iFS Femtosecond Laser System (NCT NCT01713660)

NCT ID: NCT01713660

Last Updated: 2025-02-04

Results Overview

Evaluation of incisions created as programmed and measurement in mm. Data reported will be based on intended incision size (as programmed) vs. achieved incision size (as measured).

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

37 participants

Primary outcome timeframe

Day 0, Operative (Within 2 hours of incision creation)

Results posted on

2025-02-04

Participant Flow

Subjects were recruited from private medical practices from October to December 2012

No preassignment details

Participant milestones

Participant milestones
Measure
FS Corneal Incisions
iFS Femtosecond Laser : corneal incisions created by the femtosecond laser
Overall Study
STARTED
37
Overall Study
COMPLETED
37
Overall Study
NOT COMPLETED
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Corneal Incisions With the IntraLase iFS Femtosecond Laser System

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
FS Corneal Incisions
n=37 Participants
iFS Femtosecond Laser : corneal incisions created by the femtosecond laser
Age, Categorical
<=18 years
0 Participants
n=5 Participants
Age, Categorical
Between 18 and 65 years
15 Participants
n=5 Participants
Age, Categorical
>=65 years
22 Participants
n=5 Participants
Age, Continuous
66 years
STANDARD_DEVIATION 6 • n=5 Participants
Sex: Female, Male
Female
15 Participants
n=5 Participants
Sex: Female, Male
Male
22 Participants
n=5 Participants
Region of Enrollment
United States
37 participants
n=5 Participants

PRIMARY outcome

Timeframe: Day 0, Operative (Within 2 hours of incision creation)

Evaluation of incisions created as programmed and measurement in mm. Data reported will be based on intended incision size (as programmed) vs. achieved incision size (as measured).

Outcome measures

Outcome measures
Measure
FS Corneal Incisions
n=37 eyes
iFS Femtosecond Laser : corneal incisions created by the femtosecond laser
Demonstration That the Femtosecond Laser Consistently Produces Desired Incisions.
Achieved Clear Corneal Incision (CCI) Measurement
2.75 mm
Standard Deviation 0.09
Demonstration That the Femtosecond Laser Consistently Produces Desired Incisions.
Intended CCI Incision Size (as programmed)
2.74 mm
Standard Deviation 0.08

SECONDARY outcome

Timeframe: Day 0, Operative

Surgeon questionnaire (completed at the end of each surgery and the end of each surgical day): Were incisions created as intended?

Outcome measures

Outcome measures
Measure
FS Corneal Incisions
n=37 Participants
iFS Femtosecond Laser : corneal incisions created by the femtosecond laser
Surgeon Assessment of Workflow
97.3 percentage of yes answers

SECONDARY outcome

Timeframe: Day 0 (performed immediately post-incision creation), Day 1

Demonstration of no wound leakage as measured by Seidel test at slit lamp with fluorscein dye. A negative Seidel test result indicates no wound leakage.

Outcome measures

Outcome measures
Measure
FS Corneal Incisions
n=37 eyes
iFS Femtosecond Laser : corneal incisions created by the femtosecond laser
Percent of Seidel Staining
100 percentage of eyes with negative Seidel

Adverse Events

FS Corneal Incisions

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Carrie Garufis

AMO

Phone: 7145663728

Results disclosure agreements

  • Principal investigator is a sponsor employee Clinical Trial Agreement including "Neither Institution nor Principal Investigator shall have any right to publish or present any information or results concerning the Study without express written consent of Sponsor. Under no circumstances shall Institution or Principal Investigator publish or disclose any of Sponsor's proprietary information, as defined by the CDAs, without Sponsor's prior written approval."
  • Publication restrictions are in place

Restriction type: OTHER