Trial Outcomes & Findings for Effects of Symbicort on the Ventilatory Kinematics (NCT NCT01712854)

NCT ID: NCT01712854

Last Updated: 2016-09-02

Results Overview

Our objective is to measure baseline, post treatment and post exercise spirometry and evaluate exercise dynamic hyperinflation before and after treatment using OEP. We hypothesize that budesonide/formoterol fumarate dihydrate will decrease dynamic hyperinflation as measured by OEP.

Recruitment status

TERMINATED

Study phase

PHASE4

Target enrollment

9 participants

Primary outcome timeframe

2 hours

Results posted on

2016-09-02

Participant Flow

The principal investigator has left the institution. Attempts to contact the PI have been unsuccessful. Columbia will never have access to the data. Thus, data will not be analyzed. The only information available is the number of participants who started and completed the study, which was last reported to and approved by the IRB in February 2013.

Participant milestones

Participant milestones
Measure
Active Medication or Placebo
Data per arm is not available. Columbia will never have access to this data.
Overall Study
STARTED
9
Overall Study
COMPLETED
8
Overall Study
NOT COMPLETED
1

Reasons for withdrawal

Reasons for withdrawal
Measure
Active Medication or Placebo
Data per arm is not available. Columbia will never have access to this data.
Overall Study
Physician Decision
1

Baseline Characteristics

Effects of Symbicort on the Ventilatory Kinematics

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Active Medication or Placebo
n=9 Participants
Data per arm is not available. Columbia will never have access to this data.
Age, Customized
Between 40 and 75 years
9 participants
n=5 Participants
Sex/Gender, Customized
Male and Female
9 participants
n=5 Participants
Region of Enrollment
United States
9 participants
n=5 Participants

PRIMARY outcome

Timeframe: 2 hours

Population: The principal investigator has left the institution. Attempts to contact the PI have been unsuccessful. Columbia will never have access to the data. Thus, data will not be analyzed. The only information available is the number of participants who started and completed the study, which was last reported to and approved by the IRB in February 2013.

Our objective is to measure baseline, post treatment and post exercise spirometry and evaluate exercise dynamic hyperinflation before and after treatment using OEP. We hypothesize that budesonide/formoterol fumarate dihydrate will decrease dynamic hyperinflation as measured by OEP.

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: 2 hours

Population: The principal investigator has left the institution. Attempts to contact the PI have been unsuccessful. Columbia will never have access to the data. Thus, data will not be analyzed. The only information available is the number of participants who started and completed the study, which was last reported to and approved by the IRB in February 2013.

Our secondary objective is to evaluate duration of steady state exercise and exercise capacity before and after treatment. Our secondary hypothesis is that decreases in dynamic hyperinflation during exercise will lead to improvements in dyspnea with exercise, and allow for increases in exercise capacity.

Outcome measures

Outcome data not reported

Adverse Events

Active Medication or Placebo

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

CU PRS Administrator

Columbia University

Phone: 212-342-1643

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place