Safety and Efficacy of the Inspiromatic Inhaler in Comparison to the Aerolizer Inhaler When Delivering Formoterol

NCT ID: NCT01711086

Last Updated: 2012-10-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

PHASE1/PHASE2

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-10-31

Study Completion Date

2012-12-31

Brief Summary

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Double-blind study, randomized, controlled, and crossover. Study recruited 30 volunteers with stable asthma aged 8-18 years. Participants will perform lung function as part of the routine follow-up then will receive a Foradil 12mcg either with an Aerolizer (a standard dry powder inhaler) or with the Inspiromatic (an active, breath synchronized innovative inhaler). 3-60 days later participants will receive the same drug through the other inhaler.

Pre and post treatment (15 min, 30 min, 60 min) Lung function results, drug levels in the blood, vital signs and side effects will be recorded.

Detailed Description

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Conditions

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Asthma

Keywords

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asthma dry powder inhaler

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Caregivers Investigators

Study Groups

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Inspiromatic followed by Aerolizer

volunteers will perform lung function pre and post Formoterol (a bronchodilator) inhalation. They will use either the Inspiromatic dry powder inhalers the delivery device. 3-60 days later participants will receive the same drug through the Aerolizer dry powder inhaler.

Group Type ACTIVE_COMPARATOR

Inspiromatic followed by Aerolizer

Intervention Type DEVICE

Participants will receive Formoterol (Foradil) 12mcg via the Inspiromatic dry powder inhaler while performing lung function instead of getting it via the Foradil Aerolizer

Aerolizer followed by Inspiromatic

volunteers will perform lung function pre and post Formoterol (a bronchodilator) inhalation. They will use either the Aerolizer dry powder inhalers the delivery device. 3-60 days later participants will receive the same drug through the Inspiromatic dry powder inhaler.

Group Type ACTIVE_COMPARATOR

Aerolizer Followed by Inspiromatic

Intervention Type DEVICE

Participants will receive Formoterol (Foradil) 12mcg via the Foradil Aerolizer inhaler while performing lung function as part of the and not differ from other routine follow-up

Interventions

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Aerolizer Followed by Inspiromatic

Participants will receive Formoterol (Foradil) 12mcg via the Foradil Aerolizer inhaler while performing lung function as part of the and not differ from other routine follow-up

Intervention Type DEVICE

Inspiromatic followed by Aerolizer

Participants will receive Formoterol (Foradil) 12mcg via the Inspiromatic dry powder inhaler while performing lung function instead of getting it via the Foradil Aerolizer

Intervention Type DEVICE

Other Intervention Names

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Foradil Inhaler Inspiromatic dry powder experimental inhaler

Eligibility Criteria

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Inclusion Criteria

* Children 8-18 years with Asthma
* 50\<FEV1\<80
* Can perform Spirometry

Exclusion Criteria

* Poor cooperation
* Pregnancy
* Milk Allergy
* Other lung disease
* Prior familiarity with Aerolizer
Minimum Eligible Age

8 Years

Maximum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Schneider Children's Medical Center, Israel

OTHER

Sponsor Role collaborator

Inspiromedical Inc

UNKNOWN

Sponsor Role collaborator

Guy Steuer

OTHER

Sponsor Role lead

Responsible Party

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Guy Steuer

Guy Steuer, M.D.

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Guy Steuer, M.D.

Role: PRINCIPAL_INVESTIGATOR

Schneider Children Hospital

Locations

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Schneider Children Hospital

Petah Tikva, , Israel

Site Status

Countries

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Israel

Central Contacts

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Guy Steuer, M.D.

Role: CONTACT

Phone: +972524249925

Email: [email protected]

Hanna Blau, M.D.

Role: CONTACT

Phone: +97239253654

Email: [email protected]

Facility Contacts

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Guy Steuer, M.D.

Role: primary

Other Identifiers

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0401-11-RMC

Identifier Type: -

Identifier Source: org_study_id