Web-based CBT for Recent Veterans Experiencing Problems With Trauma Symptoms or Alcohol/Drug Use

NCT ID: NCT01710943

Last Updated: 2012-10-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

PHASE1/PHASE2

Total Enrollment

216 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-09-30

Study Completion Date

2014-06-30

Brief Summary

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The proposed study involves developing and evaluating an interactive, web-based CBT intervention for OEF/OIF Veterans with hazardous or problematic substance use and PTSD symptoms (PTSD or subsyndromal PTSD). The intervention will address the special culture and experiences of the investigators targeted population (OEF/OIF Veterans). The web-based CBT intervention includes 24 modules, to be used across 24 sessions targeting OEF/OIF Veterans with hazardous or problematic substance use and PTSD symptoms. The investigators ask participants to complete 2 sessions per week (one module per session) for 12 weeks. The first 18 modules to be completed across 18 sessions (9 weeks) are considered core modules relevant to all Veterans in the target population. These modules are designed to reduce posttraumatic stress symptoms as well as reduce and prevent the escalation of problematic substance use. The remaining 6 module topics are considered "optional" and are used based on the interest and clinical need of various sub-groups of VA patients. The study includes initial input as well as feedback on a beta version from experts who have worked with OEF/OIF veterans with PTSD and substance abuse problems as well as input/feedback from the target population (the Veterans themselves). In addition to presenting content grounded in evidence-based CBT interventions, the program also employs state of the art technologies to deliver module content grounded in evidence-based learning principles, including Computer-Assisted Instruction, Computer Simulation and other interactive exercises.

Detailed Description

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Conditions

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Post-Traumatic Stress Symptoms Problematic Use of Alcohol or Other Drugs

Keywords

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Web-based CBT PTSD Alcohol Misuse Substance Misuse Integrated Primary Care OEF/OIF Veterans

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Web-based Cognitive Behavioral Treatment

Participants who are randomly assigned to the treatment condition will receive the same standard care as those in the control condition and they will also receive access to the web-based CBT intervention. Participants in this condition will be asked to complete 24 CBT sessions, 2 sessions/topics per week for 12 weeks. Participants will be asked to complete the 18 "core modules" of the program during the first 9 weeks of the trial and then to re-visit important modules and complete optional modules of their choice during the final 3 weeks of the trial.

Group Type EXPERIMENTAL

Web-based Cognitive Behavioral Treatment

Intervention Type BEHAVIORAL

Participants in this condition will be asked to complete 24 CBT sessions, 2 sessions/topics per week for 12 weeks. We expect that each session will be approximately 30 minutes in duration. Participants will be asked to complete the 18 "core modules" of the program during the first 9 weeks of the trial and then to re-visit important modules and complete optional modules of their choice during the final 3 weeks of the trial. They can choose to do this using a designated computer in a private room at their local VA or can complete these sessions in the privacy of their own home with their personally-owned computers. Participants can choose to complete each session on any day/time of their choosing in a given week.

Treatment as Usual

TAU consists of the usual Veterans Integrated Service Network 2 (VISN) primary care services. As we have described, all of the participants will be recruited from patients presenting for treatment typically for physical complaints in primary care clinics in VA's VISN 2 (Upstate NY). VISN 2 officially practices a co-located, collaborative care model of integrated (behavioral health and physical health) in its primary care clinics. This integrated model has been implemented widely in both VA and non-VA primary care clinics in the United States .

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Web-based Cognitive Behavioral Treatment

Participants in this condition will be asked to complete 24 CBT sessions, 2 sessions/topics per week for 12 weeks. We expect that each session will be approximately 30 minutes in duration. Participants will be asked to complete the 18 "core modules" of the program during the first 9 weeks of the trial and then to re-visit important modules and complete optional modules of their choice during the final 3 weeks of the trial. They can choose to do this using a designated computer in a private room at their local VA or can complete these sessions in the privacy of their own home with their personally-owned computers. Participants can choose to complete each session on any day/time of their choosing in a given week.

Intervention Type BEHAVIORAL

Other Intervention Names

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Web-based CBT

Eligibility Criteria

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Inclusion Criteria

1. At least 18 years of age
2. An OEF or OIF veteran (verified via CPRS)
3. Screen positive on the Audit-C (\>=3 for women or \>= 4 for men) OR screen positive on the PC-PTSD (\>=3).
4. Currently receiving primary medical care at a VA Medical Center (verified via CPRS)


1. At least 18 years of age
2. An OEF or OIF veteran (verified via CPRS)
3. Hazardous or harmful substance use as measured by one of the following:

* AUDIT-C score of \>=3 (for women) or \>= 4 (for men) OR
* DAST score of \>=2 OR
* Have exited a controlled environment (e.g., detoxification unit, hospital, or correctional facility) within 30 days of screening AND within 30 days prior to entering the controlled environment report:

i. heavy drinking (\>3 drinks for women or \> 4 drinks for men on one or more days), or ii.use of any illegal drugs, iii.or misuse of prescription drugs (use in excess of the directions or any non-medical use)
4. Screen positive on the PC-PTSD (\>=2).
5. Currently receiving primary medical care at a VA Medical Center (verified via CPRS)


1. At least 18 years of age
2. An OEF or OIF veteran (verified via CPRS)
3. Hazardous or harmful substance use as measured by one of the following:

* AUDIT score of \>=7 (for women) or \>= 8 (for men) OR
* DAST score of \>=2 OR
* Have exited a controlled environment (e.g., detoxification unit, hospital, or correctional facility) within 30 days of screening AND within 30 days prior to entering the controlled environment report:

i. heavy drinking (\>3 drinks for women or \> 4 drinks for men on1 or more days) or ii. use of any illegal drugs iii. misuse of prescription drugs (use in excess of the directions or any non-medical use)
4. Determined to have diagnostic-level or PTSD (1 A symptom, 1 B symptom, 3 C symptoms AND 2 D symptoms) or subthreshold PTSD (1 A symptom, 1 B symptom, 3 C symptoms OR 2 D symptoms) on the Clinician Administered PTSD Scale (CAPS).
5. Currently receiving primary medical care at a VA Medical Center (verified via CPRS)

Exclusion Criteria

1. Insufficient ability to understand or provide informed consent
2. Lack sufficient ability to use English to participate in the consent process,
3. Current plan or intent to harm themselves as measured with the suicide assessment in Appendix D after the consent process.

Phase 2: Feedback Sessions


1. Insufficient ability to understand or provide informed consent
2. Lack sufficient ability to use English to participate in the consent process, the computerized intervention or the assessments.
3. Current plan or intent to harm themselves as measured with the suicide assessment in Appendix D administered after the consent process.

Phase 3: Randomized Clinical Trial


1. Plans to move out of area within the next three months
2. Currently enrolled in a substance abuse treatment program or receiving treatment for PTSD from a mental health professional (verified via CPRS).
3. Insufficient ability to understand or provide informed consent
4. Lack sufficient ability to use English to participate in the consent process, the computerized intervention or the assessments.
5. In need of alcohol detoxification as determined by a score of \> 15 on the Clinical Institute Withdrawal Assessment for Alcohol (CIWA-Ar).
6. Current plan or intent to harm themselves as measured with the suicide assessment in Appendix D administered after the consent process.
7. Medical chart diagnosis of a current psychotic disorder, including schizophrenia or bi-polar disorder
8. Cognitive impairment specified by a medical chart diagnosis. Diagnoses include dementia and moderate to severe traumatic brain injury (TBI). Patients with mild TBI will not be excluded. The Second Level TBI Assessment present in patient medical records can be used to verify the severity of TBI.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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The VA Western New York Healthcare System

FED

Sponsor Role collaborator

Syracuse VA Medical Center

FED

Sponsor Role collaborator

National Development and Research Institutes, Inc.

OTHER

Sponsor Role lead

Responsible Party

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Andrew Rosenblum

Director, Institute for Treatment and Services Research

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Andrew Rosenblum, Ph.D.

Role: PRINCIPAL_INVESTIGATOR

National Development and Research Institutes, Inc.

Stephen Maisto, Ph.D.

Role: PRINCIPAL_INVESTIGATOR

Syracuse University

Locations

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Buffalo VA Medical Center

Buffalo, New York, United States

Site Status RECRUITING

Syracuse VA Medical Center

Syracuse, New York, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Kyle Possemato, Ph.D.

Role: CONTACT

Phone: 315-425-4400

Email: [email protected]

Michelle Acosta, Ph.D.

Role: CONTACT

Phone: 212-845-4535

Email: [email protected]

Other Identifiers

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R01AA020181

Identifier Type: NIH

Identifier Source: org_study_id

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