Learning Theory to Improve Obesity Treatment

NCT ID: NCT01708785

Last Updated: 2017-10-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

230 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-10-31

Study Completion Date

2017-09-30

Brief Summary

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The purpose of this study is to optimize an obesity treatment program targeting overweight 8-12 year old children using "Cue Exposure Training".

Detailed Description

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The goal of the Cue Exposure program is to train children to resist cues to eat unhealthy foods. Through a series of experimental studies, the investigators will evaluate how many weekly treatment visits there should be, whether children should be exposed to a single food or multiple foods during treatment, whether to use partial reinforcement or not, whether visits should be daily or weekly, and whether the exposures should be in single or multiple contexts. The investigators will be recruiting parent-child dyads in the San Diego community to participate in 8 to 16 weekly or daily treatment sessions either in their home, community center, or our lab, depending on the treatment arm. Parents and children will complete baseline and post-treatment assessments consisting of collecting psychophysiological data, completing laboratory tasks, and completing questionnaires. The investigators will be evaluating which treatment condition reduces overeating (as measured by our laboratory tasks).

Conditions

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Obesity

Keywords

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obesity overweight overweight children overweight parents overeating eating in the absence of hunger families with overweight child body mass index BMI weight childhood obesity treatment cue exposure treatment cravings habituation to food cues psychophysiological response to food cues intervention experiments family based treatment behavioral treatment

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Single context

Subjects will be exposed to food cues in a single context.

Group Type ACTIVE_COMPARATOR

Partial Reinforcement - Enhanced Cue Exposure Treatment

Intervention Type BEHAVIORAL

Subjects will take random additional tastes of the food during cue exposure treatment.

Partial Reinforcement -Consistent Cue Exposure Treatment

Intervention Type BEHAVIORAL

Subjects will consistently take the same tastes of the food during cue exposure treatment.

Multiple contexts

Subjects will be exposed to food cues in multiple contexts.

Group Type EXPERIMENTAL

Partial Reinforcement - Enhanced Cue Exposure Treatment

Intervention Type BEHAVIORAL

Subjects will take random additional tastes of the food during cue exposure treatment.

Partial Reinforcement -Consistent Cue Exposure Treatment

Intervention Type BEHAVIORAL

Subjects will consistently take the same tastes of the food during cue exposure treatment.

8 treatment sessions

Subjects receive 8 treatment sessions.

Group Type ACTIVE_COMPARATOR

Single food Cue Exposure Treatment

Intervention Type BEHAVIORAL

Subjects will be exposed to the same set of 4 foods in each cue exposure treatment session.

Multiple food Cue Exposure Treatment

Intervention Type BEHAVIORAL

Subjects will be exposed to a different set of 4 foods in each cue exposure treatment session.

16 treatment sessions

Subjects receive 16 treatment sessions

Group Type EXPERIMENTAL

Single food Cue Exposure Treatment

Intervention Type BEHAVIORAL

Subjects will be exposed to the same set of 4 foods in each cue exposure treatment session.

Multiple food Cue Exposure Treatment

Intervention Type BEHAVIORAL

Subjects will be exposed to a different set of 4 foods in each cue exposure treatment session.

Interventions

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Single food Cue Exposure Treatment

Subjects will be exposed to the same set of 4 foods in each cue exposure treatment session.

Intervention Type BEHAVIORAL

Multiple food Cue Exposure Treatment

Subjects will be exposed to a different set of 4 foods in each cue exposure treatment session.

Intervention Type BEHAVIORAL

Partial Reinforcement - Enhanced Cue Exposure Treatment

Subjects will take random additional tastes of the food during cue exposure treatment.

Intervention Type BEHAVIORAL

Partial Reinforcement -Consistent Cue Exposure Treatment

Subjects will consistently take the same tastes of the food during cue exposure treatment.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Response to an advertisement for the study,
* An overweight or obese child in the family who is between the ages of 8 and 13,
* The 8-13 year old child must be above the 85th BMI % for age and gender,
* Parent willing to participate and attend all meetings,
* Parent who can read at a minimum of a 5th grade level in English,
* Parent and child willing to commit to attendance and assessments,
* Child who eats in the absence of hunger.

Exclusion Criteria

* Major child psychiatric disorder diagnoses,
* An obese child over the 99.9th BMI %
* Child or parent diagnoses of diabetes for which physician supervision of diet is needed or diagnosis of serious current physical diseases (such as cancer, multiple sclerosis, lupus) which could significantly decrease their ability to participate in the intervention (parent report),
* Child taking a medication that can affect cognitive functioning, such as attention, concentration, or mental status.
* Family with restrictions on types of food, such as food allergies, or religious or ethnic practices that limit the foods available in the home (these restrictions affect their ability participate in the food exposures because it would limit the variety of foods available to do exposures with),
* Child with an active eating disorder (based on parent and child self-report)
* Major parent psychiatric or eating disorder.
Minimum Eligible Age

8 Years

Maximum Eligible Age

13 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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National Institutes of Health (NIH)

NIH

Sponsor Role collaborator

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NIH

Sponsor Role collaborator

University of California, San Diego

OTHER

Sponsor Role lead

Responsible Party

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Kerri Boutelle

Associate Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Kerri Boutelle, Ph.D.

Role: PRINCIPAL_INVESTIGATOR

UCSD

Locations

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Center for Health Eating and Activity Research

La Jolla, California, United States

Site Status

Countries

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United States

References

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Boutelle KN, Zucker NL, Peterson CB, Rydell SA, Cafri G, Harnack L. Two novel treatments to reduce overeating in overweight children: a randomized controlled trial. J Consult Clin Psychol. 2011 Dec;79(6):759-71. doi: 10.1037/a0025713.

Reference Type BACKGROUND
PMID: 22122291 (View on PubMed)

Epstein LH, Myers MD, Raynor HA, Saelens BE. Treatment of pediatric obesity. Pediatrics. 1998 Mar;101(3 Pt 2):554-70.

Reference Type BACKGROUND
PMID: 12224662 (View on PubMed)

Nederkoorn C, Smulders FT, Jansen A. Cephalic phase responses, craving and food intake in normal subjects. Appetite. 2000 Aug;35(1):45-55. doi: 10.1006/appe.2000.0328.

Reference Type BACKGROUND
PMID: 10896760 (View on PubMed)

Nederkoorn C, Jansen A. Cue reactivity and regulation of food intake. Eat Behav. 2002 Spring;3(1):61-72. doi: 10.1016/s1471-0153(01)00045-9.

Reference Type BACKGROUND
PMID: 15001020 (View on PubMed)

Other Identifiers

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1R01DK094475-01A1

Identifier Type: NIH

Identifier Source: secondary_id

View Link

120431

Identifier Type: -

Identifier Source: org_study_id