Feasibility Study: Compare the Effectiveness Between Two Pain Medications When Used Prior to Ultherapy™ Treatments

NCT ID: NCT01708473

Last Updated: 2017-11-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-07-31

Study Completion Date

2012-02-29

Brief Summary

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This study will compare the effectiveness of two pain medications for reducing discomfort during an Ultherapy treatment.

Detailed Description

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This trial is a prospective, single-site, double-blinded, randomized trial. All study subjects will receive a full face and neck Ultherapy treatment. Subjects will be randomized to receive one of two pain medications prior to treatment. Each subject will be asked to rate the level of discomfort during the Ultherapy treatment. All study subjects will be followed for 90 days following treatment.

Conditions

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Skin Laxity

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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Advil with Ultherapy

Subjects randomized to this study arm will receive Advil prior to an Ulthera System Treatment.

Group Type ACTIVE_COMPARATOR

Advil

Intervention Type DRUG

One (1) tablet 800 mg Advil one hour prior to treatment.

Ulthera System Treatment

Intervention Type DEVICE

Focused ultrasound energy delivered below the surface of the skin

Lortab with Ultherapy

Subjects randomized to this study arm will receive Lortab prior to an Ulthera System Treatment.

Group Type ACTIVE_COMPARATOR

Lortab

Intervention Type DRUG

One (1) tablet 10/500 mg of Lortab one hour prior to treatment.

Ulthera System Treatment

Intervention Type DEVICE

Focused ultrasound energy delivered below the surface of the skin

Interventions

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Advil

One (1) tablet 800 mg Advil one hour prior to treatment.

Intervention Type DRUG

Lortab

One (1) tablet 10/500 mg of Lortab one hour prior to treatment.

Intervention Type DRUG

Ulthera System Treatment

Focused ultrasound energy delivered below the surface of the skin

Intervention Type DEVICE

Other Intervention Names

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Ulthera® System Ultherapy™ Treatment Ulthera, Inc. Ultrasound treatment for skin tightening

Eligibility Criteria

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Inclusion Criteria

* Male or female, aged 30 to 65 years
* Subject in good health
* Skin laxity on the upper and lower face and neck
* Understands and accepts the obligation not to undergo any other procedures in the areas to be treated through the followup period

Exclusion Criteria

* Known sensitivity to ibuprofen, acetaminophen, or opiates
* Presence of an active systemic or local skin disease that may affect wound healing
* Severe solar elastosis
* Excessive subcutaneous fat in the face and neck
* Excessive skin laxity on the face and neck
* Significant scarring in areas to be treated
* Significant open facial wounds or lesions
* Severe or cystic acne on the face
* Presence of a metal stent or implant in the facial area to be treated
Minimum Eligible Age

30 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Ulthera, Inc

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Hema Sundaram, MD

Role: PRINCIPAL_INVESTIGATOR

Dermatology, Cosmetic & Laser Surgery

Locations

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Dermatology, Cosmetic & Laser Surgery

Rockville, Maryland, United States

Site Status

Countries

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United States

Other Identifiers

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ULT-123

Identifier Type: -

Identifier Source: org_study_id