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The MURDOCK Study Registry and Biorepository Horizon 1.5

NCT ID: NCT01708408

Last Updated: 2025-11-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Total Enrollment

50000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-02-28

Study Completion Date

2026-12-31

Brief Summary

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The MURDOCK Study Community Registry and Biorepository (Horizon 1.5) aims to create a large-scale community registry and biorepository that can be used as a vehicle for future health services, epidemiologic, clinical trials and other omics-related research.

Detailed Description

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The MURDOCK Study Community Registry and Biorepository's activities include enrolling approximately 50,000 participants who live in Cabarrus County and/or Kannapolis, North Carolina. Participants must consent to (1) use of the data provided by the participant through completion of the Participant Registry Questionnaire for epidemiologic population characterization, (2) annual contact to update their MURDOCK Horizon 1.5 database record, (3) release of their medical information, including but not limited to demographic information, problem lists, medications, social and family history, and results of laboratory and other testing modalities from pre-existing paper or electronic health records or electronic health records that may become available in the future, (4) provision of a blood and urine sample, and (5) contact up to four times/year to request participation in additional research studies.

Conditions

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Chronic Disease Healthy Volunteers

Keywords

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biorepository biobank registry community biospecimens volunteers chronic disease longitudinal blood electronic health records follow-up

Study Design

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Observational Model Type

OTHER

Study Time Perspective

PROSPECTIVE

Study Groups

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community

Biomarker studies

Intervention Type GENETIC

Interventions

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Biomarker studies

Intervention Type GENETIC

Eligibility Criteria

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Inclusion Criteria

1. A resident of Cabarrus County and/or the city of Kannapolis (and surrounding regions) for 6 or more months of the year
2. At least 18 years of age
3. Able to understand and give written informed consent, or have a legal guardian or caregiver present to give informed consent by proxy (assent from a participant between ages 12-18 will be obtained when their parent or legal guardian consents on their behalf).
4. Willing and able to participate in all 5 components of the registry and biorepository as described above in Section III
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Duke University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Kristin M Newby, MD

Role: PRINCIPAL_INVESTIGATOR

Duke University

Locations

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Duke Clinical Translational Science Institute-MURDOCK Study

Kannapolis, North Carolina, United States

Site Status

Countries

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United States

References

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Tenenbaum JD, Christian V, Cornish MA, Dolor RJ, Dunham AA, Ginsburg GS, Kraus VB, McHutchison JG, Nahm ML, Newby LK, Svetkey LP, Udayakumar K, Califf RM. The MURDOCK Study: a long-term initiative for disease reclassification through advanced biomarker discovery and integration with electronic health records. Am J Transl Res. 2012;4(3):291-301. Epub 2012 Jul 23.

Reference Type BACKGROUND
PMID: 22937207 (View on PubMed)

Related Links

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http://www.murdock-study.org

MURDOCK Study website

Other Identifiers

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Pro00011196

Identifier Type: -

Identifier Source: org_study_id