Study of the Effect of Low Level Laser Light Therapy on Reducing the Appearance of Cellulite in the Thighs and Buttocks.

NCT ID: NCT01702259

Last Updated: 2015-12-11

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

68 participants

Study Classification

INTERVENTIONAL

Study Start Date

2009-10-31

Study Completion Date

2012-09-30

Brief Summary

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The purpose of this study is to determine whether the application of green diode low level laser light therapy is effective in reducing the appearance of cellulite in the thighs and buttocks.

Detailed Description

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Cellulite is a common term used to describe superficial pockets of trapped fat, which causes uneven dimpling or "orange peel" skin. It appears in 90% of post-adolescent women. In advanced stages of cellulite, heaviness and pain may occur.

Currently available treatments for cellulite have minimal to no demonstrable effect and some involve risky invasive procedures. Therefore, the potential advantages of the application of low level laser light therapy to reduce the appearance of cellulite over current treatment options include a risk free procedure that is non-invasive and pain free. Since low level laser light within the green spectrum has been proven to increase the synthesis of collagen, it is believed that its application may serve to decrease the appearance of cellulite by tightening the skin. Moreover, newly synthesized collagen may alter the irregular pattern of the connective tissue responsible for the formation of cellulite.

Conditions

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Cellulite

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

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Erchonia Scanner device (GLS)

The Erchonia® GLS device is made up of six independent diodes, each emitting 17 milliwatts (mW), 532 nanometer (nm) of green laser light.

Group Type EXPERIMENTAL

Erchonia Scanner device (GLS)

Intervention Type DEVICE

The Erchonia® GLS device is made up of six independent diodes, each emitting 17 milliwatts (mW), 532 nanometer (nm) of green laser light.

Placebo device

Inactive Erchonia GLS device

Group Type SHAM_COMPARATOR

Placebo device

Intervention Type DEVICE

Inactive Erchonia GLS.

Interventions

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Erchonia Scanner device (GLS)

The Erchonia® GLS device is made up of six independent diodes, each emitting 17 milliwatts (mW), 532 nanometer (nm) of green laser light.

Intervention Type DEVICE

Placebo device

Inactive Erchonia GLS.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Areas for which cellulite appearance reduction is being sought are the bilateral thighs and buttocks
* Clinical cellulite gradation of Stage II or III on the Nurnberger-Muller scale for each treatment area
* PI or P2 on the American Society of Anesthesiologists (ASA) Physical Status Classification System
* Willing and able to abstain from partaking in any treatment other than the study procedure to promote cellulite appearance reduction/body contouring/weight loss during the study
* Willing and able to maintain regular diet and exercise regimen without effecting significant change in either direction during the study
* Willing and able to maintain regular medication schedule, as is medically feasible, during the study

Exclusion Criteria

* Clinical cellulite gradation of Stage 0 or I on the Nurnberger Muller Scale (NMS) for either one or both thighs/buttocks
* P3 or P4 or P5 or P6 on the ASA Physical Status Classification System
* Weight fluctuation greater than 10 pounds in the prior month
* Previous attempt(s) to reduce cellulite in the study treatment areas over the past 6 months
* Prior surgical intervention to the treatment areas, for any reason
* Medical, physical or other contraindications for cellulite reduction/body contouring/weight loss
* Current use of medication(s) known to affect weight levels and/or cause bloating or swelling and for which abstinence during the study is not safe or medically prudent
* Any medical condition known to affect weight levels, cause bloating or swelling
* Diagnosis of, and/or taking medication for, irritable bowel syndrome
* Active infection, wound or other external trauma to the study treatment areas
* Dermatitis or significant scarring in the study treatment areas
* Medical, physical, or other contraindications for, or known sensitivity to, light therapy
* Diabetes dependent on insulin or oral hypoglycemic medications
* Known cardiovascular disease
* Cardiac surgeries
* History of deep venous thrombosis, arterial disease of the legs
* Pregnant, breast feeding, or planning pregnancy prior to study end
* Serious mental health illness or psychiatric hospitalization in past 2 years
* Developmental disability or cognitive impairment that would impact study participation
* Involved in litigation/receiving disability benefits related to the parameters of the study
* Participation in research in the past 30 days
Minimum Eligible Age

18 Years

Maximum Eligible Age

55 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Erchonia Corporation

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Gregory C Roche, D.O.

Role: PRINCIPAL_INVESTIGATOR

Robert F Jackson, M.D.

Role: PRINCIPAL_INVESTIGATOR

Locations

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Surgeon's Inc.

Marion, Indiana, United States

Site Status

Bloomfield Laser and Cosmetic Surgery Center

Bloomfield Hills, Michigan, United States

Site Status

Countries

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United States

Other Identifiers

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EMCTE002

Identifier Type: -

Identifier Source: org_study_id